Pharmacology & Neuroscience

Research output

Research output per year 1973 2000 2001 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2023

• 114901 Citations
• 147 h-index
• 1977 Article
• 171 Review article
• 50 Chapter
• 49 Comment/debate
• 76 More
  • 27 Editorial
  • 19 Short survey
  • 13 Letter
  • 10 Conference contribution
  • 2 Book
  • 2 Foreword/postscript
  • 2 Conference article
  • 1 Paper

Research output per year

Research output per year

Search results

• GTPase acceleration as the rate-limiting step in Arabidopsis G protein-coupled sugar signaling

  Johnston, C. A., Taylor, J. P., Gao, Y., Kimple, A. J., Grigston, J. C., Chen, J. G., Siderovski, D. P., Jones, A. M. & Willard, F. S., 30 Oct 2007, In: Proceedings of the National Academy of Sciences of the United States of America. 104, 44, p. 17317-17322 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Arabidopsis Proteins 100%
  • Heterotrimeric GTP-Binding Proteins 76%
  • GTP Phosphohydrolases 65%
  • Guanosine Triphosphate 60%
  • GTP-Binding Proteins 56%

• Hypoperfusion induces overexpression of β-amyloid precursor protein mRNA in a focal ischemic rodent model

  Shi, J., Yang, S. H., Stubley, L., Day, A. L. & Simpkins, J. W., 17 Jan 2000, In: Brain Research. 853, 1, p. 1-4 4 p.

  Research output: Contribution to journal › Article › peer-review

  • Amyloid beta-Protein Precursor 100%
  • Rodentia 71%
  • Cerebrovascular Circulation 50%
  • Messenger RNA 49%
  • Stroke 47%

• Involvement of p38 MAPK in reactive astrogliosis induced by ischemic stroke

  Roy Choudhury, G., Ryou, M. G., Poteet, E., Wen, Y., He, R., Sun, F., Yuan, F., Jin, K. & Yang, S. H., 10 Mar 2014, In: Brain Research. 1551, p. 45-58 14 p.

  Research output: Contribution to journal › Article › peer-review

  • p38 Mitogen-Activated Protein Kinases 100%
  • Stroke 66%
  • Glial Fibrillary Acidic Protein 53%
  • Astrocytes 44%
  • Middle Cerebral Artery Infarction 35%

• Increased endoplasmic reticulum stress in human glaucomatous trabecular meshwork cells and tissues

  Peters, J. C., Bhattacharya, S., Clark, A. F. & Zode, G. S., 2015, In: Investigative Ophthalmology and Visual Science. 56, 6, p. 3860-3868 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Trabecular Meshwork 100%
  • Endoplasmic Reticulum Stress 83%
  • Transcription Factor CHOP 40%
  • glucose-regulated proteins 27%
  • Activating Transcription Factor 4 24%

• Neuroglobin protein is upregulated in Alzheimer's disease

  Sun, F., Mao, X. O., Xie, L., Greenberg, D. A. & Jin, K., 1 Jan 2013, In: Journal of Alzheimer's Disease. 36, 4, p. 659-663 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Neuroglobin 100%
  • dementia 60%
  • Alzheimer Disease 46%
  • Proteins 22%
  • Amyloidogenic Proteins 13%

• Electrophysiological properties of subventricular zone cells in adult mouse brain

  Lai, B., Mao, X. O., Xie, L., Chang, S. Y., Xiong, Z. G., Jin, K. & Greenberg, D. A., 22 Jun 2010, In: Brain Research. 1340, p. 96-105 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Lateral Ventricles 100%
  • Brain 44%
  • Neurogenesis 32%
  • 4-Aminopyridine 23%
  • Tetraethylammonium 23%

• Anti-connective tissue growth factor antibody treatment reduces Extracellular matrix production in Trabecular meshwork and Lamina Cribrosa cells

  Wallace, D. M., Clark, A. F., Lipson, K. E., Andrews, D., Crean, J. K. & O'Brien, C. J., 7 Nov 2013, In: Investigative Ophthalmology and Visual Science. 54, 13, p. 7836-7848 13 p.

  Research output: Contribution to journal › Article › peer-review

  • FG 3019 100%
  • Trabecular Meshwork 75%
  • Connective Tissue Growth Factor 75%
  • Glaucoma 53%
  • Extracellular Matrix 47%

• Validation of a serum screen for alzheimer's disease across assay platforms, species, and tissues

  O'Bryant, S. E., Xiao, G., Zhang, F., Edwards, M., German, D. C., Yin, X., Como, T., Reisch, J., Huebinger, R. M., Graff-Radford, N., Dickson, D., Barber, R., Hall, J., O'Suilleabhain, P. & Grammas, P., 2014, In: Journal of Alzheimer's Disease. 42, 4, p. 1325-1335 11 p.

  Research output: Contribution to journal › Article › peer-review

  • dementia 100%
  • Alzheimer Disease 77%
  • Serum 45%
  • Parkinson Disease 33%
  • Support Vector Machine 24%

• Fluorescent protein-labeled glucocorticoid receptor alpha isoform trafficking in cultured human trabecular meshwork cells.

  Dibas, A., Jiang, M., Fudala, R., Gryczynski, I., Gryczynski, Z., Clark, A. F. & Yorio, T., 2012, In: Investigative ophthalmology & visual science. 53, 6, p. 2938-2950 13 p.

  Research output: Contribution to journal › Article › peer-review

  • glucocorticoid receptor alpha 100%
  • Trabecular Meshwork 78%
  • red fluorescent protein 65%
  • Protein Isoforms 47%
  • Dexamethasone 28%

• Social enrichment attenuates nigrostriatal lesioning and reverses motor impairment in a progressive 1-methyl-2-phenyl-1,2,3,6-tetrahydropyridine (MPTP) mouse model of Parkinson's disease

  Goldberg, N. R. S., Fields, V., Pflibsen, L., Salvatore, M. F. & Meshul, C. K., Mar 2012, In: Neurobiology of Disease. 45, 3, p. 1051-1067 17 p.

  Research output: Contribution to journal › Article › peer-review

  • Pyrrolidines 100%
  • Parkinson Disease 50%
  • Tyrosine 3-Monooxygenase 33%
  • Putamen 24%
  • Pars Compacta 16%

• Proteomic and immunochemical characterization of a role for stathmin in adult neurogenesis

  Jin, K., Mao, X. O., Cottrell, B., Schilling, B., Xie, L., Row, R. H., Sun, Y., Peel, A., Childs, J., Gendeh, G., Gibson, B. W. & Greenberg, D. A., Feb 2004, In: FASEB Journal. 18, 2, p. 287-299 13 p.

  Research output: Contribution to journal › Article › peer-review

  • Stathmin 100%
  • Neurogenesis 68%
  • Proteomics 59%
  • Differential in Gel Electrophoresis 34%
  • Antisense Oligonucleotide 29%

• RGS21, a regulator of taste and mucociliary clearance?

  Kimple, A. J., Garland, A. L., Cohen, S. P., Setola, V., Willard, F. S., Zielinski, T., Lowery, R. G., Tarran, R. & Siderovski, D. P., Mar 2014, In: Laryngoscope. 124, 3, p. E56-E63

  Research output: Contribution to journal › Article › peer-review

  • GTP-Binding Protein Regulators 100%
  • Mucociliary Clearance 90%
  • Aversive Agents 49%
  • Mucous Membrane 42%
  • Guanosine Triphosphate 42%

• Issues in disclosing a diagnosis of dementia

  Cornett, P. F. & Hall, J. R., May 2008, In: Archives of Clinical Neuropsychology. 23, 3, p. 251-256 6 p.

  Research output: Contribution to journal › Article › peer-review

  • dementia 100%
  • Dementia 83%
  • ethical concerns 57%
  • Mentally Ill Persons 28%
  • Disclosure 27%

• Matrix Mechanotransduction via Yes-Associated Protein in Human Lamina Cribrosa Cells in Glaucoma

  Murphy, R., Irnaten, M., Hopkins, A., O'Callaghan, J., Stamer, W. D., Clark, A. F., Wallace, D. & O'Brien, C. J., Jan 2022, In: Investigative Ophthalmology and Visual Science. 63, 1, 16.

  Research output: Contribution to journal › Article › peer-review

  • Human YAP1 (Yes-associated) protein 100%
  • Glaucoma 45%
  • Proteins 17%
  • Verteporfin 13%
  • alpha 1 chain collagen type I 5%

• A depressive endophenotype for predicting cognitive decline among mexican American adults and elders

  Johnson, L. A., Gamboa, A., Vintimilla, R., Edwards, M., Hall, J., Weiser, B., Yadav, M., Dickensheets, T. & O'Bryant, S. E., 23 Aug 2016, In: Journal of Alzheimer's Disease. 54, 1, p. 201-206 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Endophenotypes 100%
  • Mexican Americans 97%
  • Cognitive Dysfunction 61%
  • cognitive impairment 61%
  • Memory 43%

• Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTEN

  Stambolic, V., Suzuki, A., De la Pompa, J. L., Brothers, G. M., Mirtsos, C., Sasaki, T., Ruland, J., Penninger, J. M., Siderovski, D. P. & Mak, T. W., 2 Oct 1998, In: Cell. 95, 1, p. 29-39 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Cell Viability 100%
  • Cell Survival 76%
  • phosphatidylinositol 3,4,5-triphosphate 73%
  • Phosphorylation 69%
  • Tensins 65%

• Factor structure of the geriatric depression scale in cognitively impaired older adults

  Hall, J. & Davis, T. E., 1 Jan 2010, In: Clinical Gerontologist. 33, 1, p. 39-48 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Geriatrics 84%
  • cognitive impairment 72%
  • Elderly 59%
  • Depression 58%
  • Cognitive Dysfunction 48%

• Ac-YVAD-CMK inhibits pyroptosis and improves functional outcome after intracerebral hemorrhage

  Lin, X., Ye, H., Siaw-Debrah, F., Pan, S., He, Z., Ni, H., Xu, Z., Jin, K., Zhuge, Q. & Huang, L., 2018, In: BioMed Research International. 2018, 3706047.

  Research output: Contribution to journal › Article › peer-review

  • N-acetyl-tyrosyl-valyl-alanyl-aspartyl chloromethyl ketone 100%
  • Intracerebral 88%
  • Pyroptosis 72%
  • Cerebral Hemorrhage 58%
  • Cell Death 58%

• Alterations in phospholipid catabolism in Mycobacterium tuberculosis lysX mutant

  Maloney, E., Lun, S., Stankowska, D., Guo, H., Rajagoapalan, M., Bishai, W. R. & Madiraju, M. V., 2011, In: Frontiers in Microbiology. 2, FEB

  Research output: Contribution to journal › Article › peer-review

  • Cardiolipins 100%
  • Mycobacterium tuberculosis 78%
  • Phospholipids 72%
  • Membrane Potentials 59%
  • phosphatidylethanolamine 48%

• Ocular-specific ER stress reduction rescues glaucoma in murine glucocorticoid-induced glaucoma

  Zode, G. S., Sharma, A. B., Lin, X., Searby, C. C., Bugge, K., Kim, G. H., Clark, A. F. & Sheffield, V. C., 2014, In: Journal of Clinical Investigation. 124, 5, p. 1956-1965 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Ocular Hypertension 100%
  • Glaucoma 90%
  • Glucocorticoids 86%
  • Dexamethasone 73%
  • Eye 59%

• Definition of the anterior choroidal artery territory in rats using intraluminal occluding technique

  He, Z., Yang, S. H., Naritomi, H., Yamawaki, T., Liu, Q., King, M. A., Day, A. L. & Simpkins, J. W., 15 Dec 2000, In: Journal of the Neurological Sciences. 182, 1, p. 16-28 13 p.

  Research output: Contribution to journal › Article › peer-review

  • Arteries 100%
  • Internal Capsule 65%
  • Infarction 56%
  • Cerebral Infarction 53%
  • Lateral Hypothalamic Area 42%

• Neuroglobin attenuates β-amyloid neurotoxicity in vitro and transgenic Alzheimer phenotype in vivo

  Khan, A. A., Xiao, O. M., Banwait, S., Jin, K. & Greenberg, D. A., 27 Nov 2007, In: Proceedings of the National Academy of Sciences of the United States of America. 104, 48, p. 19114-19119 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Neuroglobin 100%
  • Amyloid 57%
  • Phenotype 36%
  • N-Methylaspartate 27%
  • In Vitro Techniques 26%

• Structural determinants for GoLoco-induced inhibition of nucleotide release by Gα subunits

  Kimple, R. J., Kimple, M. E., Betts, L., Sondek, J. & Siderovski, D. P., 25 Apr 2002, In: Nature. 416, 6883, p. 878-881 4 p.

  Research output: Contribution to journal › Article › peer-review

  • GTP-Binding Proteins 100%
  • Nucleotides 80%
  • RGS Proteins 77%
  • Viperidae 67%
  • Heterotrimeric GTP-Binding Proteins 67%

• Role of C/EBP homologous protein in retinal ganglion cell death after ischemia/reperfusion injury

  Nashine, S., Liu, Y., Kim, B. J., Clark, A. F. & Pang, I. H., 20 Nov 2015, In: Investigative Ophthalmology and Visual Science. 56, 1, p. 221-231 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Transcription Factor CHOP 100%
  • Retinal Ganglion Cells 78%
  • Reperfusion Injury 66%
  • Cell Death 52%
  • Reperfusion 26%

• Existence of the canonical wnt signaling pathway in the human trabecular meshwork

  Mao, W., Cameron Millar, J., Wang, W. H., Silverman, S. M., Liu, Y., Wordinger, R. J., Rubin, J. S., Pang, I. H. & Clark, A. F., Oct 2012, In: Investigative Ophthalmology and Visual Science. 53, 11, p. 7043-7051 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Trabecular Meshwork 100%
  • Wnt Signaling Pathway 85%
  • frizzled related protein-1 58%
  • Luciferases 19%
  • Catenins 17%