Pharmacology & Neuroscience

Research output

Research output per year 1973 2000 2001 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2023

• 114956 Citations
• 147 h-index
• 1977 Article
• 171 Review article
• 50 Chapter
• 49 Comment/debate
• 76 More
  • 27 Editorial
  • 19 Short survey
  • 13 Letter
  • 10 Conference contribution
  • 2 Book
  • 2 Foreword/postscript
  • 2 Conference article
  • 1 Paper

Research output per year

Research output per year

Search results

• GTPase acceleration as the rate-limiting step in Arabidopsis G protein-coupled sugar signaling

  Johnston, C. A., Taylor, J. P., Gao, Y., Kimple, A. J., Grigston, J. C., Chen, J. G., Siderovski, D. P., Jones, A. M. & Willard, F. S., 30 Oct 2007, In: Proceedings of the National Academy of Sciences of the United States of America. 104, 44, p. 17317-17322 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Arabidopsis Proteins 100%
  • Heterotrimeric GTP-Binding Proteins 76%
  • GTP Phosphohydrolases 65%
  • Guanosine Triphosphate 60%
  • GTP-Binding Proteins 56%

• G protein signaling modulator-3 inhibits the inflammasome activity of NLRP3

  Giguère, P. M., Gall, B. J., Ezekwe, E. A. D., Laroche, G., Buckley, B. K., Kebaier, C., Wilson, J. E., Ting, J. P., Siderovski, D. P. & Duncan, J. A., 28 Nov 2014, In: Journal of Biological Chemistry. 289, 48, p. 33245-33257 13 p.

  Research output: Contribution to journal › Article › peer-review

  • Pyrin Domain 100%
  • NLR Proteins 98%
  • Inflammasomes 80%
  • GTP-Binding Proteins 67%
  • Interleukin-1 46%

• Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTEN

  Stambolic, V., Suzuki, A., De la Pompa, J. L., Brothers, G. M., Mirtsos, C., Sasaki, T., Ruland, J., Penninger, J. M., Siderovski, D. P. & Mak, T. W., 2 Oct 1998, In: Cell. 95, 1, p. 29-39 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Cell Viability 100%
  • Cell Survival 76%
  • phosphatidylinositol 3,4,5-triphosphate 73%
  • Phosphorylation 69%
  • Tensins 65%

• PKC modulation of GABA_A receptor endocytosis and function is inhibited by mutation of a dileucine motif within the receptor β2 subunit

  Herring, D., Huang, R. Q., Singh, M., Dillon, G. H. & Leidenheimer, N. J., Feb 2005, In: Neuropharmacology. 48, 2, p. 181-194 14 p.

  Research output: Contribution to journal › Article › peer-review

  • GABA-A Receptors 100%
  • Endocytosis 94%
  • Mutation 52%
  • Dynamins 41%
  • Chlorides 33%

• Insomnia and mental health in college students

  Taylor, D. J., Gardner, C. E., Bramoweth, A. D., Williams, J. M., Roane, B. M., Grieser, E. A. & Tatum, J. I., Apr 2011, In: Behavioral Sleep Medicine. 9, 2, p. 107-116 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Sleep Initiation and Maintenance Disorders 100%
  • Mental Health 74%
  • Students 66%
  • mental health 65%
  • young adult 31%

• Fidelity of G protein β-subunit association by the G protein γ-subunit-like domains of RGS6, RGS7, and RGS11

  Snow, B. E., Betts, L., Mangion, J., Sondek, J. & Siderovski, D. P., 25 May 1999, In: Proceedings of the National Academy of Sciences of the United States of America. 96, 11, p. 6489-6494 6 p.

  Research output: Contribution to journal › Article › peer-review

  • RGS Proteins 100%
  • Protein Subunits 73%
  • GTP-Binding Proteins 64%
  • GTP-Binding Protein Regulators 48%
  • Tryptophan 34%

• Receptor-selective effects of endogenous RGS3 and RGS5 to regulate mitogen-activated protein kinase activation in rat vascular smooth muscle cells

  Wang, Q., Liu, M., Mullah, B., Siderovski, D. P. & Neubig, R. R., 12 Jul 2002, In: Journal of Biological Chemistry. 277, 28, p. 24949-24958 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Catalytic RNA 100%
  • Mitogen-Activated Protein Kinases 75%
  • Vascular Smooth Muscle 74%
  • Smooth Muscle Myocytes 66%
  • RGS Proteins 50%

• Single Nucleotide Polymorphisms in Chemosensory Pathway Genes GNB3, TAS2R19, and TAS2R38 Are Associated with Chronic Rhinosinusitis

  Purnell, P. R., Addicks, B. L., Zalzal, H. G., Shapiro, S., Wen, S., Ramadan, H. H., Setola, V. & Siderovski, D. P., 1 Aug 2019, In: International Archives of Allergy and Immunology. 180, 1, p. 72-77 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Aversive Agents 100%
  • Single Nucleotide Polymorphism 90%
  • Gene Frequency 52%
  • Genes 43%
  • G-Protein-Coupled Receptors 27%

• Dynamic regulation of RGS2 suggests a novel mechanism in G-protein signaling and neuronal plasticity

  Ingi, T., Krumins, A. M., Chidiac, P., Brothers, G. M., Chung, S., Snow, B. E., Barnes, C. A., Lanahan, A. A., Siderovski, D. P., Ross, E. M., Gilman, A. G. & Worley, P. F., 15 Sep 1998, In: Journal of Neuroscience. 18, 18, p. 7178-7188 11 p.

  Research output: Contribution to journal › Article › peer-review

  • GTP-Binding Protein Regulators 100%
  • GTP-Binding Proteins 66%
  • Neuronal Plasticity 63%
  • GTP Phosphohydrolases 38%
  • Messenger RNA 38%

• Effect of elevated intraocular pressure on endothelin-1 in a rat model of glaucoma

  Prasanna, G., Hulet, C., Desai, D., Krishnamoorthy, R. R., Narayan, S., Brun, A. M., Suburo, A. M. & Yorio, T., Jan 2005, In: Pharmacological Research. 51, 1, p. 41-50 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Endothelin-1 100%
  • Intraocular Pressure 90%
  • Glaucoma 87%
  • Optic Disk 61%
  • Optic Nerve 57%

• Dopamine release during cocaine self-administration in rats: effect of SCH23390

  Egilmez, Y., Jung, M. E., Lane, J. D. & Emmett-Oglesby, M. W., 1 Dec 1995, In: Brain Research. 701, 1-2, p. 142-150 9 p.

  Research output: Contribution to journal › Article › peer-review

  • SCH 23390 100%
  • Self Administration 91%
  • Cocaine 76%
  • Dopamine 64%
  • Stearates 14%

• A high soy diet enhances neurotropin receptor and Bcl-X_L gene expression in the brains of ovariectomized female rats

  Lovekamp-Swan, T., Glendenning, M. L. & Schreihofer, D. A., 23 Jul 2007, In: Brain Research. 1159, 1, p. 54-66 13 p.

  Research output: Contribution to journal › Article › peer-review

  • neurotropin 100%
  • Estrogens 46%
  • Diet 38%
  • Gene Expression 33%
  • Brain 27%

• Feeding-induced stimulation of luteinizing hormone secretion in male rhesus monkeys is not dependent on a rise in blood glucose concentration

  Schreihofer, D. A., Renda, F. & Cameron, J. L., 1996, In: Endocrinology. 137, 9, p. 3770-3776 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Luteinizing Hormone 100%
  • Macaca mulatta 98%
  • Blood Glucose 77%
  • Fasting 64%
  • Glucose 58%

• Nicotine enhances inhibition of mouse vagal motor neurons by modulating excitability of premotor GABAergic neurons in the nucleus tractus solitarii

  Xu, H., Boychuk, J. A., Boychuk, C. R., Uteshev, V. V. & Smith, B. N., 2015, In: Journal of Neurophysiology. 113, 4, p. 1165-1174 10 p.

  Research output: Contribution to journal › Article › peer-review

  • GABAergic Neurons 100%
  • Solitary Nucleus 99%
  • Nicotine 80%
  • Motor Neurons 78%
  • Nicotinic Receptors 66%

• Brain-derived neurotrophic factor for high-throughput evaluation of selective Sigma-1 receptor ligands

  Dalwadi, D. A., Kim, S., Schetz, J., Schreihofer, D. A. & Kim, S., 1 Jan 2022, In: Journal of Pharmacological and Toxicological Methods. 113, 107129.

  Research output: Contribution to journal › Article › peer-review

  • sigma-1 receptor 100%
  • Brain-Derived Neurotrophic Factor 67%
  • Ligands 45%
  • Agent Interacting With Transmitter, Hormone or Drug Receptor 35%
  • Ligand 27%

• Delayed puberty and estrogen resistance in a woman with estrogen receptor α variant

  Quaynor, S. D., Stradtman, E. W., Kim, H. G., Shen, Y., Chorich, L. P., Schreihofer, D. A. & Layman, L. C., 2013, In: New England Journal of Medicine. 369, 2, p. 164-171 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Delayed Puberty 100%
  • Estrogen Receptors 64%
  • Estrogens 56%
  • Mutation 38%
  • Androgen Receptors 24%

• Cholecystokinin induces Fos expression in catecholaminergic neurons of the macaque monkey caudal medulla

  Schreihofer, D. A., Cameron, J. L., Verbalis, J. G. & Rinaman, L., 3 Oct 1997, In: Brain Research. 770, 1-2, p. 37-44 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Sincalide 100%
  • Cholecystokinin 98%
  • Macaca 93%
  • Haplorhini 77%
  • Neurons 51%

• Regulation of neuronal function by choline and 4OH-GTS-21 through α7 nicotinic receptors

  Uteshev, V. V., Meyer, E. M. & Papke, R. L., 1 Apr 2003, In: Journal of Neurophysiology. 89, 4, p. 1797-1806 10 p.

  Research output: Contribution to journal › Article › peer-review

  • 3-(4-hydroxy-2-methoxybenzylidene)anabaseine 100%
  • Nicotinic Receptors 49%
  • Choline 48%
  • Neurons 9%
  • Lateral Hypothalamic Area 6%

• Central inflammatory response to experimental stroke is inhibited by a neuroprotective dose of dietary soy

  Shambayati, M., Patel, M., Ma, Y., Cunningham, R. L. & Schreihofer, D. A., 17 Dec 2014, In: Brain Research. 1593, p. 76-82 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Isoflavones 100%
  • Middle Cerebral Artery Infarction 58%
  • Stroke 54%
  • Brain Ischemia 52%
  • Innate Immunity 48%

• Allosteric modulati on of nicotinic acetylcholine receptors: The concept and therapeutic trends

  Uteshev, V. V., 1 Apr 2016, In: Current Pharmaceutical Design. 22, 14, p. 1986-1997 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Nicotinic Receptors 100%
  • Acetylcholine 96%
  • Cholinergic 92%
  • Cholinergic Agents 50%
  • Antiinflammatory 34%

• Retina-derived fetuin (RDF): Analysis by immunocytochemistry, reverse transcriptase-polymerase chain reaction and Southern blot

  Sheedlo, H. J., Krishnamoorthy, R., Nelson, T., Agarwal, N., Liu, J., Roque, R. S., Wordinger, R. J., Jaynes, C. D., Brun-Zinkelnagel, A. M., O'Brian, P., Aschenbrenner, J. E. & Turner, J. E., Dec 1999, In: Current Eye Research. 19, 6, p. 465-471 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Fetuins 100%
  • Southern Blotting 70%
  • Reverse Transcriptase Polymerase Chain Reaction 65%
  • Retina 55%
  • Immunohistochemistry 44%

• Endothelin-1, endothelin A and B receptor expression and their pharmacological properties in GFAP negative human lamina cribrosa cells

  Rao, V. R., Krishnamoorthy, R. R. & Yorio, T., Jun 2007, In: Experimental eye research. 84, 6, p. 1115-1124 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Endothelin B Receptors 100%
  • Endothelin A Receptors 93%
  • Endothelin-1 74%
  • Pharmacology 46%
  • BQ 610 22%

• Estrogen receptor-α (ERα), but not ERβ, modulates estrogen stimulation of the ERα-truncated variant, TERP-1

  Schreihofer, D. A., Rowe, D. F., Rissman, E. F., Scordalakes, E. M., Gustafsson, J. Å. & Shupnik, M. A., 1 Nov 2002, In: Endocrinology. 143, 11, p. 4196-4202 7 p.

  Research output: Contribution to journal › Article › peer-review

  • TERP-1 100%
  • Estrogen Receptors 42%
  • Estrogens 37%
  • Messenger RNA 10%
  • Testosterone 8%

• Histamine decreases myogenic tone in rat cerebral arteries by H₂-receptor-mediated K_V channel activation, independent of endothelium and cyclic AMP

  Jarajapu, Y. P. R., Oomen, C., Uteshev, V. V. & Knot, H. J., 10 Oct 2006, In: European Journal of Pharmacology. 547, 1-3, p. 116-124 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Histamine H2 Receptors 100%
  • Cerebral Arteries 96%
  • Cyclic AMP 78%
  • Histamine 77%
  • Endothelium 70%

• Dietary genistein and equol (4′, 7 isoflavandiol) reduce oxidative stress and protect rats against focal cerebral ischemia

  Yulin, M., Sullivan, J. C. & Schreihofer, D. A., 1 Sep 2010, In: American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 299, 3, p. R871-R877

  Research output: Contribution to journal › Article › peer-review

  • Equol 100%
  • Isoflavones 80%
  • Genistein 75%
  • Brain Ischemia 63%
  • Oxidative Stress 46%