Pharmacology & Neuroscience

Research output

Research output per year 1973 2000 2001 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2023

• 114901 Citations
• 147 h-index
• 1977 Article
• 171 Review article
• 50 Chapter
• 49 Comment/debate
• 76 More
  • 27 Editorial
  • 19 Short survey
  • 13 Letter
  • 10 Conference contribution
  • 2 Book
  • 2 Foreword/postscript
  • 2 Conference article
  • 1 Paper

Research output per year

Research output per year

Search results

• Identification of a Mammalian Long Chain Fatty Acyl Elongase Regulated by Sterol Regulatory Element-binding Proteins

  Moon, Y. A., Shah, N. A., Mohapatra, S., Warrington, J. A. & Horton, J. D., 30 Nov 2001, In: Journal of Biological Chemistry. 276, 48, p. 45358-45366 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Sterol Regulatory Element Binding Proteins 100%
  • Sterol 72%
  • Fatty Acids 56%
  • Fatty Acid 53%
  • Fatty Acid Synthases 43%

• Treatment with an orally bioavailable prodrug of 17β-estradiol alleviates hot flushes without hormonal effects in the periphery

  Merchenthaler, I., Lane, M., Sabnis, G., Brodie, A., Nguyen, V., Prokai, L. & Prokai-Tatrai, K., 1 Aug 2016, In: Scientific Reports. 6, 30721.

  Research output: Contribution to journal › Article › peer-review

  • Estradiol 78%
  • Estrogens 74%
  • Skin Temperature 36%
  • Brain 29%
  • Tail 28%

• Selective chemoprecipitation and subsequent release of tagged species for the analysis of nitropeptides by liquid chromatography - Tandem mass spectrometry

  Prokai-Tatrai, K., Guo, J. & Prokai, L., Aug 2011, In: Molecular and Cellular Proteomics. 10, 8

  Research output: Contribution to journal › Article › peer-review

  • Tandem Mass Spectrometry 100%
  • Liquid Chromatography 95%
  • Peptides 58%
  • Peptide 52%
  • Esters 31%

• The binomial distribution and the evidence for independent action of ion channels

  Uteshev, V., 21 Aug 1993, In: Journal of Theoretical Biology. 163, 4, p. 485-489 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Binomial Distribution 100%
  • Ion Channels 96%
  • binomial distribution 87%
  • ion channels 76%
  • Binomial distribution 73%

• Measurement of acetylcholine in rat brain microdialysates by LC-isotope dilution tandem MS

  Prokai, L., Fryčák, P., Stevens, S. M. & Nguyen, V., Oct 2008, In: Chromatographia. 68, SUPPL. 1, p. S101-S105

  Research output: Contribution to journal › Article › peer-review

  • Isotopes 100%
  • Acetylcholine 99%
  • Tandem Mass Spectrometry 77%
  • Dilution 74%
  • Ion Pair Reversed Phase Chromatography 72%

• Histamine decreases myogenic tone in rat cerebral arteries by H₂-receptor-mediated K_V channel activation, independent of endothelium and cyclic AMP

  Jarajapu, Y. P. R., Oomen, C., Uteshev, V. V. & Knot, H. J., 10 Oct 2006, In: European Journal of Pharmacology. 547, 1-3, p. 116-124 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Histamine H2 Receptors 100%
  • Cerebral Arteries 96%
  • Cyclic AMP 78%
  • Histamine 77%
  • Endothelium 70%

• Differences in serotonin receptor expression in the brainstem may explain the differential ability of a serotonin agonist to block seizure-induced sudden death in DBA/2 vs. DBA/1 mice

  Faingold, C. L., Randall, M., Mhaskar, Y. & Uteshev, V. V., 18 Oct 2011, In: Brain Research. 1418, p. 104-110 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Serotonin Receptor Agonists 100%
  • Inbred DBA Mouse 95%
  • Serotonin Receptors 88%
  • Sudden Death 78%
  • Brain Stem 68%

• Brain-targeted chemical delivery of [Leu², Pip³]-TRH: Synthesis and biological evaluation

  Yoon, S. H., Wu, J., Wu, W. M., Prokai, L. & Bodor, N., May 2000, In: Bioorganic and Medicinal Chemistry. 8, 5, p. 1059-1063 5 p.

  Research output: Contribution to journal › Article › peer-review

  • prolyl oligopeptidase 100%
  • Brain 91%
  • barbituric acid 80%
  • Time 66%
  • Pharmacological Metabolism 48%

• Combinatorial lead optimization of a neuropeptide FF antagonist

  Prokai, L., Prokai-Tatrai, K., Zharikova, A., Li, X. & Rocca, J. R., 10 May 2001, In: Journal of Medicinal Chemistry. 44, 10, p. 1623-1626 4 p.

  Research output: Contribution to journal › Article › peer-review

  • Neuropeptide FF 100%
  • argininamide 95%
  • phenylalanyl-leucyl-phenylalanyl-glutaminyl-prolyl-glutaminyl-arginyl-phenylalaninamide 90%
  • Proline Residue 69%
  • Proline 55%

• Improved solvent-free synthesis and structure elucidation of (E)- and (Z)-4-(arylmethylene)-3-isochromanones

  Lóránd, T., Forgó, P., Földesi, A., Ôsz, E. & Prókai, L., Sep 2002, In: European Journal of Organic Chemistry. 17, p. 2996-3003 8 p.

  Research output: Contribution to journal › Article › peer-review

  • synthesis 100%
  • aldehydes 99%
  • Aldehyde 96%
  • products 88%
  • E Isomer 83%

• Microarray analysis of iris gene expression in mice with mutations influencing pigmentation

  Trantow, C. M., Cuffy, T. L., Fingert, J. H., Kuehn, M. H. & Anderson, M. G., Jan 2011, In: Investigative Ophthalmology and Visual Science. 52, 1, p. 237-248 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Pigmentation 100%
  • Iris 97%
  • Microarray Analysis 90%
  • Gene Expression 52%
  • Mutation 49%

• Exploratory neuropharmacological evaluation of a conformationally constrained thyrotropin-releasing hormone analogue

  Teixidó, M., Prokai-Tatrai, K., Wang, X., Nguyen, V. & Prokai, L., 15 Jun 2007, In: Brain Research Bulletin. 73, 1-3, p. 103-107 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Thyrotropin-Releasing Hormone 100%
  • Peptidomimetics 87%
  • Peptides 50%
  • deamido-thyrotropin-releasing hormone 38%
  • Antidepressive Agents 35%

• Effect of chronic morphine exposure on the synaptic plasma-membrane subproteome of rats: A quantitative protein profiling study based on isotope-coded affinity tags and liquid chromatography/mass spectrometry

  Prokai, L., Zharikova, A. D. & Stevens, S. M., Feb 2005, In: Journal of Mass Spectrometry. 40, 2, p. 169-175 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Morphine 100%
  • Liquid Chromatography Mass Spectrometry (LCMS) 86%
  • Protein 34%
  • Cell Membrane Potential 28%
  • Tandem Mass Spectrometry 28%

• Long range transmission of polar effects in cholinergic 3-arylideneanabaseines. Conformations calculated by molecular modelling

  Zoltewicz, J. A., Prokai-Tatrai, K., Bloom, L. B. & Kem, W. R., 1 Jan 1993, In: Heterocycles. 35, 1, p. 171-180 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Pyrrolidines 100%
  • Molecular Conformation 95%
  • Tetrahydropyridine 85%
  • Polar Effect 81%
  • Cholinergic 76%

• Hormonal responses during orthostasis following 4 hours of head-down tilt

  Williamson, J. W., Crandall, C. G., Shi, X., Squires, W. G. & Raven, P. B., 1993, In: Aviation Space and Environmental Medicine. 64, 7, p. 606-611 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Head-Down Tilt 100%
  • Dizziness 73%
  • Head 51%
  • Arginine Vasopressin 28%
  • Renin 15%

• Reduction in lbnp tolerance following prolonged endurance exercise training

  Stevens, G. H. J., Foresman, B. H., Shi, X., Stern, S. A. & Raven, P. B., Nov 1992, In: Medicine and Science in Sports and Exercise. 24, 11, p. 1235-1244 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Lower Body Negative Pressure 100%
  • Endurance Training 86%
  • Vascular Resistance 46%
  • Exercise 44%
  • Blood Volume 40%

• Two-week normobaric intermittent-hypoxic exposures stabilize cerebral perfusion during hypocapnia and hypercapnia

  Zhang, P., Shi, X. & Downey, H. F., 14 Jul 2015, In: Experimental Biology and Medicine. 240, 7, p. 961-968 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Hypocapnia 100%
  • Hyperventilation 86%
  • Conductance 67%
  • Mass Spectrometry 63%
  • Perfusion 53%

• Cerebral vasoreactivity during hypercapnia is reset by augmented sympathetic influence

  Zhang, P., Huang, G. & Shi, X., Feb 2011, In: Journal of Applied Physiology. 110, 2, p. 352-358 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Lower Body Negative Pressure 100%
  • Hypercapnia 80%
  • Pressure 35%
  • flowable hybrid composite 20%
  • Hemodynamics 20%

• Importance of post-exercise hypotension in plasma volume restoration

  Hayes, P. M., Lucas, J. C. & Shi, X., 2000, In: Acta Physiologica Scandinavica. 169, 2, p. 115-124 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Post-Exercise Hypotension 100%
  • Plasma Volume 69%
  • Albumins 50%
  • Phenylephrine 25%
  • Serum Albumin 23%

• Carotid baroreflex responsiveness to lower body positive pressure-induced increases in central venous pressure

  Shi, X., Potts, J. T., Foresman, B. H. & Raven, P. B., 1993, In: American Journal of Physiology - Heart and Circulatory Physiology. 265, 3 34-3, p. H918-H922

  Research output: Contribution to journal › Article › peer-review

  • Central Venous Pressure 100%
  • Baroreflex 95%
  • Pressure 52%
  • Arterial Pressure 18%
  • Heart Rate 16%

• Comparison of the forearm and calf blood flow response to thermal stress during dynamic exercise

  Nishiyasu, T., Shi, X., Gillen, C. M., Mack, G. W. & Nadel, E. R., Feb 1992, In: Medicine and Science in Sports and Exercise. 24, 2, p. 213-217 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Heat-Shock Response 100%
  • Forearm 87%
  • Exercise 58%
  • Skin 38%
  • Leg 28%

• Associations of Physical Activity and Dietary Behaviors With Children's Health and Academic Problems

  Shi, X., Tubb, L., Fingers, S. T., Chen, S. & Caffrey, J. L., Jan 2013, In: Journal of School Health. 83, 1, p. 1-7 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Children's Health 100%
  • Physical Activity 99%
  • Meal 85%
  • Problem Behavior 80%
  • Confidence Interval 80%

• Effects of dynamic exercise on cardiovascular regulation during lower body negative pressure

  Nishiyasu, T., Shi, X., Gillen, C. M., Mack, G. W. & Nadel, E. R., 1993, In: Aviation Space and Environmental Medicine. 64, 6, p. 517-521 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Lower Body Negative Pressure 100%
  • stroke 79%
  • Exercise 44%
  • Stroke Volume 41%
  • regulation 40%

• Wuqinxi exercise improves hand dexterity in patients with Parkinson’s disease

  Wang, T., Xiao, G., Li, Z., Jie, K., Shen, M., Jiang, Y., Wang, Z., Shi, X. & Zhuang, J., 2020, In: Evidence-based Complementary and Alternative Medicine. 2020, 8352176.

  Research output: Contribution to journal › Article › peer-review

  • Parkinson Disease 100%
  • Hand 90%
  • Exercise 77%
  • Carbonated Beverages 52%
  • Standing Position 25%

• Effects of exercise training on the autophagy-related muscular proteins expression in ovariectomized rats

  Zhong, W., Shi, X., Yuan, H., Bu, H., Wu, L. & Wang, R., 2019, In: Frontiers in Physiology. 10, JUN, 735.

  Research output: Contribution to journal › Article › peer-review

  • Autophagy-Related Proteins 100%
  • Exercise 44%
  • Autophagy 41%
  • Ovariectomy 19%
  • Swimming 18%