Pharmacology & Neuroscience

Research output

Research output per year 1973 2000 2001 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2023

• 115082 Citations
• 147 h-index
• 1976 Article
• 171 Review article
• 50 Chapter
• 49 Comment/debate
• 75 More
  • 26 Editorial
  • 19 Short survey
  • 13 Letter
  • 10 Conference contribution
  • 2 Book
  • 2 Foreword/postscript
  • 2 Conference article
  • 1 Paper

Research output per year

Research output per year

Search results

• Multiscale imaging reveals aberrant functional connectome organization and elevated dorsal striatal arc expression in advanced age

  Colon-Perez, L. M., Turner, S. M., Lubke, K. N., Pompilus, M., Febo, M. & Burke, S. N., 1 Nov 2019, In: eNeuro. 6, 6, ENEURO.0047-19.2019.

  Research output: Contribution to journal › Article › peer-review

  • Connectome 100%
  • Corpus Striatum 69%
  • Short-Term Memory 22%
  • Immediate-Early Genes 14%
  • Psychological Adaptation 13%

• A consensus protocol for functional connectivity analysis in the rat brain

  Grandjean, J., Desrosiers-Gregoire, G., Anckaerts, C., Angeles-Valdez, D., Ayad, F., Barrière, D. A., Blockx, I., Bortel, A., Broadwater, M., Cardoso, B. M., Célestine, M., Chavez-Negrete, J. E., Choi, S., Christiaen, E., Clavijo, P., Colon-Perez, L., Cramer, S., Daniele, T., Dempsey, E., Diao, Y., & 189 othersDoelemeyer, A., Dopfel, D., Dvořáková, L., Falfán-Melgoza, C., Fernandes, F. F., Fowler, C. F., Fuentes-Ibañez, A., Garin, C., Gelderman, E., Golden, C. E. M., Guo, C. C. G., Henckens, M. J. A. G., Hennessy, L. A., Herman, P., Hofwijks, N., Horien, C., Ionescu, T. M., Jones, J., Kaesser, J., Kim, E., Lambers, H., Lazari, A., Lee, S. H., Lillywhite, A., Liu, Y., Liu, Y. Y., López -Castro, A., López-Gil, X., Ma, Z., MacNicol, E., Madularu, D., Mandino, F., Marciano, S., McAuslan, M. J., McCunn, P., McIntosh, A., Meng, X., Meyer-Baese, L., Missault, S., Moro, F., Naessens, D. M. P., Nava-Gomez, L. J., Nonaka, H., Ortiz, J. J., Paasonen, J., Peeters, L. M., Pereira, M., Perez, P. D., Pompilus, M., Prior, M., Rakhmatullin, R., Reimann, H. M., Reinwald, J., Del Rio, R. T., Rivera-Olvera, A., Ruiz-Pérez, D., Russo, G., Rutten, T. J., Ryoke, R., Sack, M., Salvan, P., Sanganahalli, B. G., Schroeter, A., Seewoo, B. J., Selingue, E., Seuwen, A., Shi, B., Sirmpilatze, N., Smith, J. A. B., Smith, C., Sobczak, F., Stenroos, P. J., Straathof, M., Strobelt, S., Sumiyoshi, A., Takahashi, K., Torres-García, M. E., Tudela, R., van den Berg, M., van der Marel, K., van Hout, A. T. B., Vertullo, R., Vidal, B., Vrooman, R. M., Wang, V. X., Wank, I., Watson, D. J. G., Yin, T., Zhang, Y., Zurbruegg, S., Achard, S., Alcauter, S., Auer, D. P., Barbier, E. L., Baudewig, J., Beckmann, C. F., Beckmann, N., Becq, G. J. P. C., Blezer, E. L. A., Bolbos, R., Boretius, S., Bouvard, S., Budinger, E., Buxbaum, J. D., Cash, D., Chapman, V., Chuang, K. H., Ciobanu, L., Coolen, B. F., Dalley, J. W., Dhenain, M., Dijkhuizen, R. M., Esteban, O., Faber, C., Febo, M., Feindel, K. W., Forloni, G., Fouquet, J., Garza-Villarreal, E. A., Gass, N., Glennon, J. C., Gozzi, A., Gröhn, O., Harkin, A., Heerschap, A., Helluy, X., Herfert, K., Heuser, A., Homberg, J. R., Houwing, D. J., Hyder, F., Ielacqua, G. D., Jelescu, I. O., Johansen-Berg, H., Kaneko, G., Kawashima, R., Keilholz, S. D., Keliris, G. A., Kelly, C., Kerskens, C., Khokhar, J. Y., Kind, P. C., Langlois, J. B., Lerch, J. P., López-Hidalgo, M. A., Manahan-Vaughan, D., Marchand, F., Mars, R. B., Marsella, G., Micotti, E., Muñoz-Moreno, E., Near, J., Niendorf, T., Otte, W. M., Pais-Roldán, P., Pan, W. J., Prado-Alcalá, R. A., Quirarte, G. L., Rodger, J., Rosenow, T., Sampaio-Baptista, C., Sartorius, A., Sawiak, S. J., Scheenen, T. W. J., Shemesh, N., Shih, Y. Y. I., Shmuel, A., Soria, G., Stoop, R., Thompson, G. J., Till, S. M., Todd, N., Van Der Linden, A., van der Toorn, A., van Tilborg, G. A. F., Vanhove, C., Veltien, A., Verhoye, M., Wachsmuth, L., Weber-Fahr, W., Wenk, P., Yu, X., Zerbi, V., Zhang, N., Zhang, B. B., Zimmer, L., Devenyi, G. A., Chakravarty, M. M. & Hess, A., Apr 2023, In: Nature Neuroscience. 26, 4, p. 673-681 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Brain 100%
  • Neurosciences 72%
  • Neuroimaging 61%
  • Datasets 53%
  • Animal Models 49%

• Dimensionless, scale invariant, edge weight metric for the study of complex structural networks

  Colon-Perez, L. M., Spindler, C., Goicochea, S., Triplett, W., Parekh, M., Montie, E., Carney, P. R., Price, C. & Mareci, T. H., 14 Jul 2015, In: PLoS ONE. 10, 7, e0131493.

  Research output: Contribution to journal › Article › peer-review

  • Weights and Measures 100%
  • Signal-To-Noise Ratio 40%
  • Seeds 35%
  • Brain 25%
  • Corpus Callosum 19%

• Imaging white matter in human brainstem

  Ford, A., Colon-Perez, L., Triplett, W. T., Gullett, J. M., Mareci, T. H. & FitzGerald, D. B., 8 Jul 2013, In: Frontiers in Human Neuroscience. JUL

  Research output: Contribution to journal › Article › peer-review

  • White Matter 100%
  • Brain Stem 98%
  • Middle Cerebellar Peduncle 49%
  • Diffusion Magnetic Resonance Imaging 36%
  • Study Guides 22%

• Reduced plasma membrane surface expression of GLAST mediates decreased glutamate regulation in the aged striatum

  Nickell, J., Salvatore, M. F., Pomerleau, F., Apparsundaram, S. & Gerhardt, G. A., Nov 2007, In: Neurobiology of Aging. 28, 11, p. 1737-1748 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Glutamic Acid 100%
  • Cell Membrane 82%
  • Inbred F344 Rats 42%
  • Biotinylation 26%
  • Amino Acid Transport System X-AG 25%

• Analysis of rabbit tear fluid using capillary electrophoresis with UV or laser-induced fluorescence detection.

  Varnell, R. J., Maitchouk, D. Y., Beuerman, R. W., Salvatore, M. F., Carlton, J. E. & Haag, A. M., 1997, In: Journal of capillary electrophoresis. 4, 1, p. 1-6 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Capillary electrophoresis 100%
  • Capillary Electrophoresis 79%
  • Electrophoresis 78%
  • Fluorescence 69%
  • Capillary Zone Electrophoresis 68%

• Sustained captopril-induced reduction in blood pressure is associated with alterations in Gut-Brain axis in the spontaneously hypertensive rat

  Yang, T., Aquino, V., Lobaton, G. O., Li, H., Colon-Perez, L., Goel, R., Qi, Y., Zubcevic, J., Febo, M., Richards, E. M., Pepine, C. J. & Raizada, M. K., 2019, In: Journal of the American Heart Association. 8, 4, e010721.

  Research output: Contribution to journal › Article › peer-review

  • Captopril 100%
  • Inbred SHR Rats 92%
  • Blood Pressure 54%
  • Brain 41%
  • Gastrointestinal Microbiome 28%

• High-field magnetic resonance imaging of the human temporal lobe

  Colon-Perez, L. M., King, M., Parekh, M., Boutzoukas, A., Carmona, E., Couret, M., Klassen, R., Mareci, T. H. & Carney, P. R., 17 Aug 2015, In: NeuroImage: Clinical. 9, p. 58-68 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Temporal Lobe 100%
  • Diffusion Magnetic Resonance Imaging 95%
  • Magnetic Resonance Imaging 71%
  • Temporal Lobe Epilepsy 62%
  • Epilepsy 45%

• Touchscreen-Based Cognitive Training Alters Functional Connectivity Patterns in Aged But Not Young Male Rats

  Gaynor, L. S., Ravi, M., Zequeira, S., Hampton, A. M., Pyon, W. S., Smith, S., Colon-Perez, L. M., Pompilus, M., Bizon, J. L., Maurer, A. P., Febo, M. & Burke, S. N., Feb 2023, In: eNeuro. 10, 2, ENEURO.0329-22.2023.

  Research output: Contribution to journal › Article › peer-review

  • Perirhinal Cortex 100%
  • Paired-Associate Learning 51%
  • Brain 50%
  • Task Performance and Analysis 36%
  • Seeds 34%

• Classification of fractional order biomarkers for anomalous diffusion using q-space entropy

  Magin, R. L., Ingo, C., Triplett, W., Colon-Perez, L. & Mareci, T. H., 2014, In: Critical Reviews in Biomedical Engineering. 42, 1, p. 63-83 21 p.

  Research output: Contribution to journal › Article › peer-review

  • Biomarkers 100%
  • Entropy 67%
  • Tissue 40%
  • Magnetic resonance 33%
  • Imaging techniques 24%

• The tyrosine kinase inhibitor genistein directly inhibits GABA(A) receptors

  Huang, R. Q., Fang, M. J. & Dillon, G. H., 6 Apr 1999, In: Molecular Brain Research. 67, 1, p. 177-183 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Genistein 100%
  • GABA-A Receptors 90%
  • Protein-Tyrosine Kinases 76%
  • gamma-Aminobutyric Acid 53%
  • lavendustin A 24%

• Oxytocin receptors are expressed by glutamatergic prefrontal cortical neurons that selectively modulate social recognition

  Tan, Y., Singhal, S. M., Harden, S. W., Cahill, K. M., Nguyen, D. T. M., Colon-Perez, L. M., Sahagian, T. J., Thinschmidt, J. S., De Kloet, A. D., Febo, M., Frazier, C. J. & Krause, E. G., 24 Apr 2019, In: Journal of Neuroscience. 39, 17, p. 3249-3263 15 p.

  Research output: Contribution to journal › Article › peer-review

  • Oxytocin Receptors 100%
  • Psychology Recognition 63%
  • Optogenetics 46%
  • Neurons 44%
  • Oxytocin 39%

• Reduced structural connectivity of the medial temporal lobe including the perforant path is associated with aging and verbal memory impairment

  Granger, S. J., Colon-Perez, L., Larson, M. S., Bennett, I. J., Phelan, M., Keator, D. B., Janecek, J. T., Sathishkumar, M. T., Smith, A. P., McMillan, L., Greenia, D., Corrada, M. M., Kawas, C. H. & Yassa, M. A., Jan 2023, In: Neurobiology of Aging. 121, p. 119-128 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Perforant Pathway 100%
  • Temporal Lobe 66%
  • Memory 52%
  • Entorhinal Cortex 35%
  • Cognitive Dysfunction 23%

• Identification of residues mediating inhibition of glycine receptors by protons

  Chen, Z. & Huang, R., Jun 2007, In: Neuropharmacology. 52, 8, p. 1606-1615 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Glycine Receptors 100%
  • Protons 74%
  • Histidine 20%
  • Glycine 18%
  • Binding Sites 13%

• Enhanced functional connectivity and volume between cognitive and reward centers of naïve rodent brain produced

  Febo, M., Blum, K., Badgaiyan, R. D., Perez, P. D., Colon-Perez, L. M., Thanos, P. K., Ferris, C. F., Kulkarni, P., Giordano, J., Baron, D. & Gold, M. S., Apr 2017, In: PLoS ONE. 12, 4, e0174774.

  Research output: Contribution to journal › Article › peer-review

  • Reward 100%
  • KB220Z 93%
  • Rodentia 85%
  • Brain 50%
  • Anterior Thalamic Nuclei 29%

• Dopamine Transporter Loss in 6-OHDA Parkinson's Model Is Unmet by Parallel Reduction in Dopamine Uptake

  Chotibut, T., Apple, D. M., Jefferis, R. & Salvatore, M. F., 29 Dec 2012, In: PLoS ONE. 7, 12, e52322.

  Research output: Contribution to journal › Article › peer-review

  • Dopamine Plasma Membrane Transport Proteins 100%
  • Oxidopamine 93%
  • Dopamine 76%
  • transporters 70%
  • uptake mechanisms 53%

• Prenatal cocaine exposure alters potassium-evoked dopamine release dynamics in rat striatum

  Salvatore, M. F., Hudspeth, O., Arnold, L. E., Wilson, P. E., Stanford, J. A., MacTutus, C. F., Booze, R. M. & Gerhardt, G. A., 2004, In: Neuroscience. 123, 2, p. 481-490 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Cocaine 100%
  • Potassium 90%
  • Dopamine 84%
  • Dopamine Plasma Membrane Transport Proteins 52%
  • Dopaminergic Neurons 44%

• Inhibition of nitric oxide synthase fails to disrupt the development of cholinergic fiber patches in the rat superior colliculus

  Mize, R. R., Scheiner, C. A., Salvatore, M. F. & Cork, R. J., Jan 1997, In: Developmental Neuroscience. 19, 3, p. 260-273 14 p.

  Research output: Contribution to journal › Article › peer-review

  • Cholinergic Fibers 100%
  • Superior Colliculi 78%
  • NADP 71%
  • Nitric Oxide Synthase 63%
  • Choline O-Acetyltransferase 48%

• Constitutive Ret signaling leads to long-lasting expression of amphetamine-induced place conditioning via elevation of mesolimbic dopamine

  Kopra, J., Villarta-Aguilera, M., Savolainen, M., Weingerl, S., Myöhänen, T. T., Rannanpää, S., Salvatore, M. F., Andressoo, J. O. & Piepponen, T. P., Jan 2018, In: Neuropharmacology. 128, p. 221-230 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Glial Cell Line-Derived Neurotrophic Factor 100%
  • Mouse Gdnf protein 86%
  • Amphetamine 82%
  • Dopamine 63%
  • Ventral Striatum 40%

• Neurochemical investigations of dopamine neuronal systems in iron-regulatory protein 2 (IRP-2) knockout mice

  Salvatore, M. F., Fisher, B., Surgener, S. P., Gerhardt, G. A. & Rouault, T., 3 Oct 2005, In: Molecular Brain Research. 139, 2, p. 341-347 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Iron Regulatory Protein 2 100%
  • Knockout Mice 51%
  • Dopamine 47%
  • Serine 34%
  • Ventral Striatum 28%

• Transient striatal GLT-1 blockade increases EAAC1 expression, glutamate reuptake, and decreases tyrosine hydroxylase phosphorylation at ser ¹⁹

  Salvatore, M. F., Davis, R. W., Arnold, J. C. & Chotibut, T., Apr 2012, In: Experimental Neurology. 234, 2, p. 428-436 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Tyrosine 3-Monooxygenase 100%
  • Corpus Striatum 88%
  • Glutamic Acid 80%
  • Phosphorylation 62%
  • dihydrokainic acid 59%

• Decreased plasma membrane expression of striatal dopamine transporter in aging

  Salvatore, M. F., Apparsundaram, S. & Gerhardt, G. A., Dec 2003, In: Neurobiology of Aging. 24, 8, p. 1147-1154 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Dopamine Plasma Membrane Transport Proteins 100%
  • Corpus Striatum 78%
  • Cell Membrane 59%
  • Ventral Tegmental Area 29%
  • Tyrosine 3-Monooxygenase 26%

• The hippocampus: detailed assessment of normative two-dimensional measurements, signal intensity, and subfield conspicuity on routine 3T T2-weighted sequences

  Middlebrooks, E. H., Quisling, R. G., King, M. A., Carney, P. R., Roper, S., Colon-Perez, L. M. & Mareci, T. H., 1 Oct 2017, In: Surgical and Radiologic Anatomy. 39, 10, p. 1149-1159 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Hippocampus 100%
  • Reference Values 33%
  • Benchmarking 22%

• Electroacupuncture Promotes Central Nervous System-Dependent Release of Mesenchymal Stem Cells

  Salazar, T. E., Richardson, M. R., Beli, E., Ripsch, M. S., George, J., Kim, Y., Duan, Y., Moldovan, L., Yan, Y., Bhatwadekar, A., Jadhav, V., Smith, J. A., McGorray, S., Bertone, A. L., Traktuev, D. O., March, K. L., Colon-Perez, L. M., Avin, K. G., Sims, E., Mund, J. A., & 24 othersCase, J., Deng, X., Kim, M. S., McDavitt, B., Boulton, M. E., Thinschmidt, J., Li Calzi, S., Fitz, S. D., Fuchs, R. K., Warden, S. J., McKinley, T., Shekhar, A., Febo, M., Johnson, P. L., Chang, L. J., Gao, Z., Kolonin, M. G., Lai, S., Ma, J., Dong, X., White, F. A., Xie, H., Yoder, M. C. & Grant, M. B., May 2017, In: Stem Cells. 35, 5, p. 1303-1315 13 p.

  Research output: Contribution to journal › Article › peer-review

  • Electroacupuncture 100%
  • Mesenchymal Stem Cells 68%
  • Central Nervous System 56%
  • Sympathetic Nervous System 51%
  • Rodentia 25%

• Functional connectivity of chronic cocaine use reveals progressive neuroadaptations in neocortical, striatal, and limbic networks

  Orsini, C. A., Colon-Perez, L. M., Heshmati, S. C., Setlow, B. & Febo, M., 1 Jul 2018, In: eNeuro. 5, 4, e0081-18.2018.

  Research output: Contribution to journal › Article › peer-review

  • Cocaine 100%
  • Corpus Striatum 97%
  • Sucrose 55%
  • Self Administration 51%
  • Brain 27%