Pharmacology & Neuroscience

2023

Clinical evaluation of fall risk in older adults who use lower-limb prostheses: A scoping review

Finco, M. G., Sumien, N. & Moudy, S. C., 2023, (Accepted/In press) In: Journal of the American Geriatrics Society.

Research output: Contribution to journal › Review article › peer-review

Comparison of locomotor stimulant and drug discrimination effects of four synthetic cathinones to commonly abused psychostimulants

Shetty, R. A., Hoch, A. C., Sumien, N., Forster, M. J. & Gatch, M. B., 2023, (Accepted/In press) In: Journal of Psychopharmacology.

Research output: Contribution to journal › Article › peer-review

Design and Synthesis of Conformationally Flexible Scaffold as Bitopic Ligands for Potent D₃-Selective Antagonists

Kim, H. Y., Lee, J. Y., Hsieh, C. J., Taylor, M., Luedtke, R. R. & Mach, R. H., Jan 2023, In: International journal of molecular sciences. 24, 1, 432.

Research output: Contribution to journal › Article › peer-review

Open Access

1 Scopus citations

Medical comorbidities and ethnicity impact plasma Alzheimer's disease biomarkers: Important considerations for clinical trials and practice

for the HABS-HD Study Team, Jan 2023, In: Alzheimer's and Dementia. 19, 1, p. 36-43 8 p.

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Modulation of nigral dopamine signaling mitigates parkinsonian signs of aging: evidence from intervention with calorie restriction or inhibition of dopamine uptake

Salvatore, M. F., Kasanga, E. A., Kelley, D. P., Venable, K. E., McInnis, T. R., Cantu, M. A., Terrebonne, J., Lanza, K., Meadows, S. M., Centner, A., Bishop, C. & Ingram, D. K., Feb 2023, In: GeroScience. 45, 1, p. 45-63 19 p.

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Plasma Biomarkers of Alzheimer's Disease Are Associated with Physical Functioning Outcomes Among Cognitively Normal Adults in the Multiethnic HABS-HD Cohort

HABS-HD Study Team, 26 Jan 2023, In: Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 78, 1, p. 9-15 7 p.

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Reduced structural connectivity of the medial temporal lobe including the perforant path is associated with aging and verbal memory impairment

Granger, S. J., Colon-Perez, L., Larson, M. S., Bennett, I. J., Phelan, M., Keator, D. B., Janecek, J. T., Sathishkumar, M. T., Smith, A. P., McMillan, L., Greenia, D., Corrada, M. M., Kawas, C. H. & Yassa, M. A., Jan 2023, In: Neurobiology of Aging. 121, p. 119-128 10 p.

Research output: Contribution to journal › Article › peer-review

Synthesis and evaluation of a new class of MIF-inhibitors in activated macrophage cells and in experimental septic shock in mice

Garai, J., Radnai, B., Vámos, E., Kovács, D., Vántus, V. B., Rumbus, Z., Pákai, E., Garami, A., Gulyás-Fekete, G., Agócs, A., Krekó, M., Zaman, K., Prókai, L., Őrfi, L., Jakus, P. B. & Lóránd, T., 5 Feb 2023, In: European Journal of Medicinal Chemistry. 247, 115050.

Research output: Contribution to journal › Article › peer-review

Open Access

Synthesis and Pharmacological Characterization of a Difluorinated Analogue of Reduced Haloperidol as a Sigma-1 Receptor Ligand

Gao, R. D., Taylor, M., McInnis, T., Chen, Z., Gori, S. S., LaPorte, H. M., Siegler, M. A., Neisewander, J. L., Mach, R. H., Singh, M., Slusher, B. S., Rais, R., Luedtke, R. R. & Tsukamoto, T., 1 Mar 2023, In: ACS Chemical Neuroscience. 14, 5, p. 947-957 11 p.

Research output: Contribution to journal › Article › peer-review

Touchscreen-Based Cognitive Training Alters Functional Connectivity Patterns in Aged But Not Young Male Rats

Gaynor, L. S., Ravi, M., Zequeira, S., Hampton, A. M., Pyon, W. S., Smith, S., Colon-Perez, L. M., Pompilus, M., Bizon, J. L., Maurer, A. P., Febo, M. & Burke, S. N., Feb 2023, In: eNeuro. 10, 2, ENEURO.0329-22.2023.

Research output: Contribution to journal › Article › peer-review

Open Access

2022

Ablation of Sphingosine Kinase 1 Protects Cornea from Neovascularization in a Mouse Corneal Injury Model

Wilkerson, J. L., Basu, S. K., Stiles, M. A., Prislovsky, A., Grambergs, R. C., Nicholas, S. E., Karamichos, D., Allegood, J. C., Proia, R. L. & Mandal, N., Sep 2022, In: Cells. 11, 18, 2914.

Research output: Contribution to journal › Article › peer-review

Open Access

A blood screening tool for detecting mild cognitive impairment and Alzheimer's disease among community-dwelling Mexican Americans and non-Hispanic Whites: A method for increasing representation of diverse populations in clinical research

for the HABLE Study Team, Jan 2022, In: Alzheimer's and Dementia. 18, 1, p. 77-87 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

9 Scopus citations

Alzheimer's Disease Genotype Frequencies Differ in Top Risk Alleles Between Mexican Americans and Non-Hispanic Whites in HABLE Cohort

Housini, M., Rao, S. R., Phillips, N. R., O'Bryant, S. E. & Barber, R. C., Dec 2022, In: Alzheimer's and Dementia. 18, S5, e067346.

Research output: Contribution to journal › Comment/debate

Analysis of a precision medicine approach to treating Parkinson's disease: Analysis of the DATATOP study

O'Bryant, S. E., Petersen, M., Zhang, F., Johnson, L., Mason, D. & Hall, J., Jan 2022, In: Parkinsonism and Related Disorders. 94, p. 15-21 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

A Novel Mouse Model of TGFβ2-Induced Ocular Hypertension Using Lentiviral Gene Delivery

Patil, S. V., Kasetti, R. B., Millar, J. C. & Zode, G. S., 1 Jul 2022, In: International journal of molecular sciences. 23, 13, 6883.

Research output: Contribution to journal › Article › peer-review

Open Access

1 Scopus citations

Anterior pituitary, sex hormones, and keratoconus: Beyond traditional targets

Karamichos, D., Escandon, P., Vasini, B., Nicholas, S. E., Van, L., Dang, D. H., Cunningham, R. L. & Riaz, K. M., May 2022, In: Progress in Retinal and Eye Research. 88, 101016.

Research output: Contribution to journal › Short survey › peer-review

9 Scopus citations

APOEε4 Genotype Is Related to Brain Amyloid Among Mexican Americans in the HABS-HD Study

The HABS-HD Study Team, 15 Jun 2022, In: Frontiers in Neurology. 13, 834685.

Research output: Contribution to journal › Article › peer-review

Open Access

1 Scopus citations

Application of Structural Retinal Biomarkers to Detect Cognitive Impairment in a Primary Care Setting

Mozdbar, S., Petersen, M., Zhang, F., Johnson, L., Tolman, A., Nyalakonda, R., Gutierrez, A. & O'Bryant, S., 2022, In: Journal of Alzheimer's Disease Reports. 6, 1, p. 749-755 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Behavioral pharmacology of five novel synthetic cannabinoids

Gatch, M. B., Tourigny, A., Shetty, R. A. & Forster, M. J., 1 Apr 2022, In: Behavioural pharmacology. 33, 23, p. 175-183 9 p.

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Brain-derived neurotrophic factor for high-throughput evaluation of selective Sigma-1 receptor ligands

Dalwadi, D. A., Kim, S., Schetz, J., Schreihofer, D. A. & Kim, S., 1 Jan 2022, In: Journal of Pharmacological and Toxicological Methods. 113, 107129.

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Cardiovascular Risk Factors and Cognitive Performance in Cognitively Normal Non-Hispanic Whites and Mexican Americans From the HABS-HD Cohort

Vintimilla, R., Nevin, T., Hall, J., Johnson, L. & O’Bryant, S., 1 Jan 2022, In: Gerontology and Geriatric Medicine. 8

Research output: Contribution to journal › Article › peer-review

Open Access

Cerebral small vessel disease alters neurovascular unit regulation of microcirculation integrity involved in vascular cognitive impairment

Yang, Q., Wei, X., Deng, B., Chang, Z., Jin, D., Huang, Y., Zhang, J. H., Yenari, M. A., Jin, K. & Wang, Q., Aug 2022, In: Neurobiology of Disease. 170, 105750.

Research output: Contribution to journal › Review article › peer-review

Open Access

3 Scopus citations

Characterization of Mild Cognitive Impairment and Dementia among Community-Dwelling Mexican Americans and Non-Hispanic Whites

HABS-HD Study Team, 2022, In: Journal of Alzheimer's Disease. 90, 2, p. 905-915 11 p.

Research output: Contribution to journal › Article › peer-review

Characterizing Plasma Biomarkers of Alzheimer's in a Diverse Community-Based Cohort: A Cross-Sectional Study of the HAB-HD Cohort

The Health and Aging Brain Study (HABS-HD) Study Team, 18 Aug 2022, In: Frontiers in Neurology. 13, 871947.

Research output: Contribution to journal › Article › peer-review

Open Access

Characterizing plasma NfL in a community-dwelling multi-ethnic cohort: Results from the HABLE study

for the HABLE Study Team, Feb 2022, In: Alzheimer's and Dementia. 18, 2, p. 240-250 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

16 Scopus citations

Characterizing region-specific glucose metabolic profile of the rodent brain using Seahorse XFe96 analyzer

Wang, L., Chaudhari, K., Winters, A., Sun, Y., Liu, R. & Yang, S. H., Jul 2022, In: Journal of Cerebral Blood Flow and Metabolism. 42, 7, p. 1259-1271 13 p.

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Cognitive dysfunction and the 25-item National Eye Institute Visual Function Questionnaire

Mozdbar, S., Alber, J., Aryal, S., Johnson, L., Moroz, A., Rashik, M., Mostafavi, A. & O'Bryant, S., 2022, In: Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring. 14, 1, e12378.

Research output: Contribution to journal › Article › peer-review

Open Access

Combination of Serum and Plasma Biomarkers Could Improve Prediction Performance for Alzheimer’s Disease

Zhang, F., Petersen, M., Johnson, L., Hall, J. & O’Bryant, S. E., Oct 2022, In: Genes. 13, 10, 1738.

Research output: Contribution to journal › Article › peer-review

Open Access

Consensus Recommendation for Mouse Models of Ocular Hypertension to Study Aqueous Humor Outflow and Its Mechanisms

McDowell, C. M., Kizhatil, K., Elliott, M. H., Overby, D. R., van Batenburg-Sherwood, J., Cameron Millar, J., Kuehn, M. H., Zode, G., Acott, T. S., Anderson, M. G., Bhattacharya, S. K., Bertrand, J. A., Borras, T., Bovenkamp, D. E., Cheng, L., Danias, J., De Ieso, M. L., Du, Y., Faralli, J. A., Fuchshofer, R., & 60 othersGanapathy, P. S., Gong, H., Herberg, S., Hernandez, H., Humphries, P., John, S. W. M., Kaufman, P. L., Keller, K. E., Kelley, M. J., Kelly, R. A., Krizaj, D., Kumar, A., Leonard, B. C., Lieberman, R. L., Liton, P., Liu, Y., Liu, K. C., Lopez, N. N., Mao, W., Mavlyutov, T., McDonnell, F., McLellan, G. J., Mzyk, P., Nartey, A., Pasquale, L. R., Patel, G. C., Pattabiraman, P. P., Peters, D. M., Raghunathan, V., Rao, P. V., Rayana, N., Raychaudhuri, U., Reina-Torres, E., Ren, R., Rhee, D., Chowdhury, U. R., Samples, J. R., Griffen Samples, E., Sharif, N., Schuman, J. S., Sheffield, V. C., Stevenson, C. H., Soundararajan, A., Subramanian, P., Sugali, C. K., Sun, Y., Toris, C. B., Torrejon, K. Y., Vahabikashi, A., Vranka, J. A., Wang, T., Willoughby, C. E., Xin, C., Yun, H., Zhang, H. F., Fautsch, M. P., Tamm, E. R., Clark, A. F., Ross Ethier, C. & Daniel Stamer, W., Feb 2022, In: Investigative Ophthalmology and Visual Science. 63, 2, 12.

Research output: Contribution to journal › Article › peer-review

Open Access

12 Scopus citations

CRISPR–Cas9: current and future utilities in ocular diseases

Yacoub, S., Raola, A. & Zode, G., 1 Jan 2022, Handbook of Basic and Clinical Ocular Pharmacology and Therapeutics. Elsevier, p. 615-623 9 p.

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

Depression is differentially related to cognitive and biomarker outcomes among Mexican Americans

The HABS-HD Study Team, 23 Aug 2022, In: Frontiers in Psychiatry. 13, 901403.

Research output: Contribution to journal › Article › peer-review

Open Access

Design, synthesis, and evaluation of functionalized 5-(4-arylpiperazin-1-yl)-N-arylpentanamides as selective dopamine D₃ receptor ligands

Blass, B. E., Chen, P. J., Taylor, M., Griffin, S. A., Gordon, J. C. & Luedtke, R. R., Jan 2022, In: Medicinal Chemistry Research. 31, 1, p. 132-145 14 p.

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Design, synthesis, and evaluation of functionalized 5-(4-arylpiperazin-1-yl)-N-quinolinyl-pentanamides as selective dopamine D₃ receptor ligands

Blass, B. E., Chen, P. J., Taylor, M., Griffin, S. A., Gordon, J. C. & Luedtke, R. R., May 2022, In: Medicinal Chemistry Research. 31, 5, p. 749-761 13 p.

Research output: Contribution to journal › Article › peer-review

Dietary genistein and 17β-estradiol implants differentially influence locomotor and cognitive functions following transient focal ischemia in middle-aged ovariectomized rats at different lengths of estrogen deprivation

Oppong-Gyebi, A., Metzger, D., Vann, P. H., Sumien, N. & Schreihofer, D. A., Aug 2022, In: Hormones and Behavior. 144, 105201.

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Early-Onset Glaucoma in egl1 Mice Homozygous for Pitx2 Mutation

Kodati, B., Merchant, S. A., Cameron Millar, J. & Liu, Y., Mar 2022, In: Biomedicines. 10, 3, 516.

Research output: Contribution to journal › Article › peer-review

Open Access

1 Scopus citations

Effect of ATP-sensitive Potassium Channel Openers on Intraocular Pressure in Ocular Hypertensive Animal Models

Chowdhury, U. R., Millar, J. C., Holman, B. H., Anderson, K. J., Dosa, P. I., Roddy, G. W. & Fautsch, M. P., Feb 2022, In: Investigative Ophthalmology and Visual Science. 63, 2, 15.

Research output: Contribution to journal › Article › peer-review

Open Access

2 Scopus citations

Enhanced Orai1-mediated store-operated Ca2+ channel/calpain signaling contributes to high glucose-induced podocyte injury

Tao, Y., Chaudhari, S., Shotorbani, P. Y., Ding, Y., Chen, Z., Kasetti, R., Zode, G. & Ma, R., 1 Jun 2022, In: Journal of Biological Chemistry. 298, 6, 101990.

Research output: Contribution to journal › Article › peer-review

Open Access

5 Scopus citations

Establishing Equivalent Aerobic Exercise Parameters Between Early-Stage Parkinson's Disease and Pink1 Knockout Rats

Salvatore, M. F., Soto, I., Kasanga, E. A., James, R., Shifflet, M. K., Doshier, K., Little, J. T., John, J., Alphonso, H. M., Cunningham, J. T. & Nejtek, V. A., 2022, In: Journal of Parkinson's Disease. 12, 6, p. 1897-1915 19 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Establishment of a Modified and Standardized Ferric Chloride-Induced Rat Carotid Artery Thrombosis Model

Lin, X., Zhao, P., Lin, Z., Chen, J., Bingwa, L. A., Siaw-Debrah, F., Zhang, P., Jin, K., Yang, S. & Zhuge, Q., 15 Mar 2022, In: ACS Omega. 7, 10, p. 8919-8927 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

1 Scopus citations

Evaluation of a Brief Sleep Intervention Designed to Improve the Sleep, Mood, and Cognitive Performance of Esports Athletes

Bonnar, D., Lee, S., Roane, B. M., Blum, D. J., Kahn, M., Jang, E., Dunican, I. C., Gradisar, M. & Suh, S., 1 Apr 2022, In: International Journal of Environmental Research and Public Health. 19, 7, 4146.

Research output: Contribution to journal › Article › peer-review

Open Access

2 Scopus citations

Expression of procollagen C-proteinase enhancer 1 in human trabecular meshwork tissues and cells

Rangan, R., Sad do Valle, R. & Tovar-Vidales, T., Dec 2022, In: Experimental eye research. 225, 109280.

Research output: Contribution to journal › Article › peer-review

Expression of stable and reliable preference and aversion phenotypes following place conditioning with psychostimulants

Shetty, R. A., Rutledge, M., LeBouf, A., Mock, J. T., Pathak, G. & Forster, M. J., Aug 2022, In: Psychopharmacology. 239, 8, p. 2593-2603 11 p.

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Global Comparative Label-Free Yeast Proteome Analysis by LC-MS/MS After High-pH Reversed-Phase Peptide Fractionation Using Solid-Phase Extraction Cartridges

Zaman, K., Pandey, P., Shulaev, V. & Prokai, L., 2022, Methods in Molecular Biology. Humana Press Inc., p. 71-84 14 p. (Methods in Molecular Biology; vol. 2396).

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

Hippocampal dentate gyrus integrity revealed with ultrahigh resolution diffusion imaging predicts memory performance in older adults

Granger, S. J., Colon-Perez, L., Larson, M. S., Phelan, M., Keator, D. B., Janecek, J. T., Sathishkumar, M. T., Smith, A. P., McMillan, L., Greenia, D., Corrada, M. M., Kawas, C. H. & Yassa, M. A., Sep 2022, In: Hippocampus. 32, 9, p. 627-638 12 p.

Research output: Contribution to journal › Article › peer-review

Hyperparameter Tuning with High Performance Computing Machine Learning for Imbalanced Alzheimer’s Disease Data

Zhang, F., Petersen, M., Johnson, L., Hall, J. & O’bryant, S. E., 1 Jul 2022, In: Applied Sciences (Switzerland). 12, 13, 6670.

Research output: Contribution to journal › Article › peer-review

Open Access

Hypoxic breathing produces more intense hypoxemia in elderly women than in elderly men

Zhao, J., Ding, Y., Kline, G. P., Zhou, Z., Mallet, R. T. & Shi, X., 26 Oct 2022, In: Frontiers in Physiology. 13, 989635.

Research output: Contribution to journal › Article › peer-review

Open Access

Hypoxic postconditioning promotes neurogenesis by modulating the metabolism of neural stem cells after cerebral ischemia

Li, H., Li, S., Ren, C., Gao, C., Li, N., Wang, C., Wang, L., Zhao, W., Ji, X. & Jin, K., Jan 2022, In: Experimental Neurology. 347, 113871.

Research output: Contribution to journal › Article › peer-review

5 Scopus citations

Latest in Cellular Pathology Research

Karamichos, D., Dec 2022, In: Cells. 11, 24, 4037.

Research output: Contribution to journal › Editorial

Open Access

Let-7 underlies metformin-induced inhibition of hepatic glucose production

Xie, D., Chen, F., Zhang, Y., Shi, B., Song, J., Chaudhari, K., Yang, S. H., Zhang, G. J., Sun, X., Taylor, H. S., Li, D. & Huang, Y., 5 Apr 2022, In: Proceedings of the National Academy of Sciences of the United States of America. 119, 14, e2122217119.

Research output: Contribution to journal › Article › peer-review

Open Access

2 Scopus citations

Long-term hypogonadism diminishes the neuroprotective effects of dietary genistein in young adult ovariectomized rats after transient focal ischemia

Oppong-Gyebi, A., Metzger, D., Doan, T., Han, J., Vann, P. H., Yockey, R. A., Sumien, N. & Schreihofer, D. A., Feb 2022, In: Journal of Neuroscience Research. 100, 2, p. 598-619 22 p.

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Pharmacology & Neuroscience

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