Research Output

2020
Open Access

Activated human astrocyte-derived extracellular vesicles modulate neuronal uptake, differentiation and firing

You, Y., Borgmann, K., Edara, V. V., Stacy, S., Ghorpade, A. & Ikezu, T., 1 Jan 2020, In : Journal of Extracellular Vesicles. 9, 1, 1706801.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Breakthroughs in medicinal chemistry: New targets and mechanisms, new drugs, new hopes-6

Vanden Eynde, J. J., Mangoni, A. A., Rautio, J., Leprince, J., Azuma, Y. T., García-Sosa, A. T., Hulme, C., Jampilek, J., Karaman, R., Li, W., Gomes, P. A. C., Hadjipavlou-Litina, D., Capasso, R., Geronikaki, A., Cerchia, L., Sabatier, J. M., Ragno, R., Tuccinardi, T., Trabocchi, A., Winum, J. Y. & 22 others, Luque, F. J., Prokai-Tatrai, K., Spetea, M., Gütschow, M., Kosalec, I., Guillou, C., Vasconcelos, M. H., Kokotos, G., Rastelli, G., De Sousa, M. E., Manera, C., Gemma, S., Mangani, S., Siciliano, C., Galdiero, S., Liu, H., Scott, P. J. H., De Los Ríos, C., Agrofoglio, L. A., Collina, S., Guedes, R. C. & Muñoz-Torrero, D., 1 Jan 2020, In : Molecules. 25, 1, 119.

Research output: Contribution to journalReview article

Open Access

Cardiovascular risk factors in Mexico and the United States: a comparative cross-sectional study between the HABLE and MHAS participants

Vintimilla, R., Reyes, M., Johnson, L., Hall, J. & O'Bryant, S., 1 Jan 2020, In : Gaceta medica de Mexico. 156, 1, p. 17-21 5 p.

Research output: Contribution to journalArticle

Open Access

Coronaridine congeners potentiate GABAA receptors and induce sedative activity in mice in a benzodiazepine-insensitive manner

Arias, H. R., Do Rego, J. L., Do Rego, J. C., Chen, Z., Anouar, Y., Scholze, P., Gonzales, E. B., Huang, R. & Chagraoui, A., 13 Jul 2020, In : Progress in Neuro-Psychopharmacology and Biological Psychiatry. 101, 109930.

Research output: Contribution to journalArticle

Effects of dietary 5-methoxyindole-2-carboxylic acid on brain functional recovery after ischemic stroke

Sumien, N., Huang, R., Chen, Z., Vann, P. H., Wong, J. M., Li, W., Yang, S., Forster, M. J. & Yan, L. J., 27 Jan 2020, In : Behavioural Brain Research. 378, 112278.

Research output: Contribution to journalArticle

Open Access

Exceptionally low likelihood of Alzheimer’s dementia in APOE2 homozygotes from a 5,000-person neuropathological study

The Alzheimer’s Disease Genetics Consortium, 1 Dec 2020, In : Nature Communications. 11, 1, 667.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Inducible rodent models of glaucoma

Pang, I. H. & Clark, A. F., Mar 2020, In : Progress in Retinal and Eye Research. 75, 100799.

Research output: Contribution to journalReview article

1 Scopus citations

Inhibition of p-mTOR represses PS1 transcription by reducing p-JNK

Das, H. K. & Hontiveros, S. S., 1 Mar 2020, In : Frontiers in Bioscience - Landmark. 25, 7, p. 1297-1304 8 p.

Research output: Contribution to journalArticle

Inhibition of p-mTOR represses transcription of PS1 and Notch 1-signaling

Das, H. K. & Hontiveros, S. S., 1 Mar 2020, In : Frontiers in Bioscience - Landmark. 25, 6, p. 1172-1183 12 p.

Research output: Contribution to journalArticle

1 Scopus citations

Intermittent Hypoxia Training for Treating Mild Cognitive Impairment: A Pilot Study

Wang, H., Shi, X., Schenck, H., Hall, J. R., Ross, S. E., Kline, G. P., Chen, S., Mallet, R. T. & Chen, P., 1 Jan 2020, In : American journal of Alzheimer's disease and other dementias. 35, p. 1533317519896725

Research output: Contribution to journalArticle

Open Access

Kynurenic acid protects against ischemia/reperfusion-induced retinal ganglion cell death in mice

Nahomi, R. B., Nam, M. H., Rankenberg, J., Rakete, S., Houck, J. A., Johnson, G. C., Stankowska, D. L., Pantcheva, M. B., Maclean, P. S. & Nagaraj, R. H., 1 Mar 2020, In : International journal of molecular sciences. 21, 5, 1795.

Research output: Contribution to journalArticle

Open Access

Long-term HIV-1 Tat Expression in the Brain Led to Neurobehavioral, Pathological, and Epigenetic Changes Reminiscent of Accelerated Aging

Zhao, X., Fan, Y., Vann, P. H., Wong, J. M., Sumien, N. & He, J. J., 1 Feb 2020, In : Aging and Disease. 11, 1, p. 93-107 15 p.

Research output: Contribution to journalReview article

Open Access

Metformin and cognition from the perspectives of sex, age, and disease

Chaudhari, K., Reynolds, C. D. & Yang, S. H., 1 Feb 2020, In : GeroScience. 42, 1, p. 97-116 20 p.

Research output: Contribution to journalReview article

Microglia exacerbate white matter injury via complement C3/C3aR pathway after hypoperfusion

Zhang, L. Y., Pan, J., Mamtilahun, M., Zhu, Y., Wang, L., Venkatesh, A., Shi, R., Tu, X., Jin, K., Wang, Y., Zhang, Z. & Yang, G. Y., 1 Jan 2020, In : Theranostics. 10, 1, p. 74-90 17 p.

Research output: Contribution to journalArticle

Open Access

New measures for COVID-19 response: a lesson from the Wenzhou experience

Ruan, L., Wen, M., Zeng, Q., Chen, C., Huang, S., Yang, S., Yang, J., Wang, J., Hu, Y., Ding, S., Zhang, Y., Zhang, H., Feng, Y., Jin, K. & ZhuGe, Q., 3 Apr 2020, (Accepted/In press) In : Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

Research output: Contribution to journalArticle

Open Access

Next generation sequencing and functional pathway analysis to understand the mechanism of action of copper-tolfenamic acid against pancreatic cancer cells

Hurtado, M., Prokai, L., Sankpal, U. T., Levesque, B., Maram, R., Chhabra, J., Brown, D. T., Gurung, R. K., Holder, A. A., Vishwanatha, J. K. & Basha, R., Feb 2020, In : Process Biochemistry. 89, p. 155-164 10 p.

Research output: Contribution to journalArticle

Open Access

Pharmacologic fibroblast reprogramming into photoreceptors restores vision

Mahato, B., Kaya, K. D., Fan, Y., Sumien, N., Shetty, R. A., Zhang, W., Davis, D., Mock, T., Batabyal, S., Ni, A., Mohanty, S., Han, Z., Farjo, R., Forster, M. J., Swaroop, A. & Chavala, S. H., 1 Jan 2020, (Accepted/In press) In : Nature.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Sex-dependent mechanisms of glucocorticoid regulation of the mouse hypothalamic corticotropin-releasing hormone gene

Heck, A. L., Thompson, M. K., Uht, R. M. & Handa, R. J., 1 Jan 2020, In : Endocrinology (United States). 161, 1

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Two-stage Bayesian GWAS of 9576 individuals identifies SNP regions that are targeted by miRNAs inversely expressed in Alzheimer's and cancer

for the Alzheimer's Disease Neuroimaging Initiative, Breast and Prostate Cancer Cohort Consortium, and Alzheimer's Disease Genetics Consortium, 1 Jan 2020, In : Alzheimer's and Dementia. 16, 1, p. 162-177 16 p.

Research output: Contribution to journalArticle

Open Access
2019

[ 99 mTc-HYNIC-N-dodecylamide]:a new hydrophobic tracer for labelling reconstituted high-density lipoproteins (rHDL) for radioimaging

Isaac-Olivé, K., Ocampo-García, B. E., Aranda-Lara, L., Santos-Cuevas, C. L., Jiménez-Mancilla, N. P., Luna-Gutiérrez, M. A., Medina, L. A., Nagarajan, B., Sabnis, N., Raut, S., Prokai, L. & Lacko, A. G., 14 Jan 2019, In : Nanoscale. 11, 2, p. 541-551 11 p.

Research output: Contribution to journalArticle

1 Scopus citations

AMPK signaling regulates the age-related decline of hippocampal neurogenesis

Wang, B. Z., Yang, J. J., Zhang, H., Smith, C. A. & Jin, K., 1 Jan 2019, In : Aging and Disease. 10, 5, p. 1058-1074 17 p.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

A novel prodrug approach for central nervous system-selective estrogen therapy

Prokai-Tatrai, K. & Prokai, L., 19 Nov 2019, In : Molecules. 24, 22, 4197.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

A novel serum free primary astrocyte culture method that mimic quiescent astrocyte phenotype

Prah, J., Winters, A., Chaudhari, K., Hersh, J., Liu, R. & Yang, S. H., 15 May 2019, In : Journal of Neuroscience Methods. 320, p. 50-63 14 p.

Research output: Contribution to journalArticle

1 Scopus citations

A proteomic signature for dementia with Lewy bodies

O'Bryant, S. E., Ferman, T. J., Zhang, F., Hall, J., Pedraza, O., Wszolek, Z. K., Como, T., Julovich, D., Mattevada, S., Johnson, L. A., Edwards, M. & Graff-Radford, N. R., Dec 2019, In : Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring. 11, p. 270-276 7 p.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

A role for Regulator of G protein Signaling-12 (RGS12) in the balance between myoblast proliferation and differentiation

Schroer, A. B., Mohamed, J. S., Willard, M. D., Setola, V., Oestreich, E. & Siderovski, D. P., 1 Jan 2019, In : PLoS ONE. 14, 8, e0216167.

Research output: Contribution to journalArticle

Open Access

Assessing Neuronal and Astrocyte Derived Exosomes From Individuals With Mild Traumatic Brain Injury for Markers of Neurodegeneration and Cytotoxic Activity

Winston, C. N., Romero, H. K., Ellisman, M., Nauss, S., Julovich, D. A., Conger, T., Hall, J. R., Campana, W., O’Bryant, S. E., Nievergelt, C. M., Baker, D. G., Risbrough, V. B. & Rissman, R. A., 2 Oct 2019, In : Frontiers in Neuroscience. 13, 1005.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Author Correction: Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing (Nature Genetics, (2019), 51, 3, (414-430), 10.1038/s41588-019-0358-2)

Alzheimer Disease Genetics Consortium (ADGC), The European Alzheimer’s Disease Initiative (EADI), Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium (CHARGE) & Genetic and Environmental Risk in AD/Defining Genetic, Polygenic and Environmental Risk for Alzheimer’s Disease Consortium (GERAD/PERADES), 1 Sep 2019, In : Nature Genetics. 51, 9, p. 1423-1424 2 p.

Research output: Contribution to journalComment/debate

Open Access

Basics on the use of acid-sensing ion channels' inhibitors as therapeutics

Dibas, J., Al-Saad, H. & Dibas, A., Mar 2019, In : Neural Regeneration Research. 14, 3, p. 395-398 4 p.

Research output: Contribution to journalReview article

1 Scopus citations

Blood-based biomarkers for Down syndrome and Alzheimer's disease: A systematic review

Petersen, M. E. & O'Bryant, S. E., 1 Jul 2019, In : Developmental Neurobiology. 79, 7, p. 699-710 12 p.

Research output: Contribution to journalReview article

3 Scopus citations

Blood-based protein predictors of dementia severity as measured by δ: Replication across biofluids and cohorts

Royall, D. R., Bishnoi, R. J., Palmer, R. F., Pavlik, V., Massman, P., Darby, E., Rodriguear, M., Ansari, A. K., DeToledo, J. C., Reddy, H., Wilms, H., Johnson, K., Perez, V., Fairchild, T., Knebl, J., O'Bryant, S. E., Hall, J. R., Johnson, L., Barber, R. C., Mains, D. & 22 others, Alvarez, L., Cullum, M., Rosenberg, R., Williams, B., Quiceno, M., Reisch, J., Hynan, L. S., Huebinger, R., Smith, J., Nguyen, T., Royall, D., Palmer, R., Polk, M., Stevens, A., Ory, M., Paydarfar, D., Bertelson, J., Woon, M., Ayres, G., Aguirre, A., Wilhelmsen, K. C. & Tilson, J. L., Dec 2019, In : Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring. 11, p. 763-774 12 p.

Research output: Contribution to journalArticle

Open Access

Blood-based systems biology biomarkers for next-generation clinical trials in Alzheimer’s disease

Alzheimer Precision Medicine Initiative (APMI), 1 Jan 2019, In : Dialogues in Clinical Neuroscience. 21, 2, p. 177-191 15 p.

Research output: Contribution to journalArticle

1 Scopus citations

Blood Biomarkers for Use in Alzheimer Disease - Moving from "if" to "how?"

O'Bryant, S. E., Sep 2019, In : JAMA Neurology. 76, 9, p. 1009-1010 2 p.

Research output: Contribution to journalEditorial

5 Scopus citations

Brain Aβ load association and sexual dimorphism of plasma BACE1 concentrations in cognitively normal individuals at risk for AD

the INSIGHT-preAD study group & Alzheimer Precision Medicine Initiative (APMI), Oct 2019, In : Alzheimer's and Dementia. 15, 10, p. 1274-1285 12 p.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Brain delivery of thyrotropin-releasing hormone via a novel prodrug approach

Prokai-Tatrai, K., De La Cruz, D. L., Nguyen, V., Ross, B. P., Toth, I. & Prokai, L., Jul 2019, In : Pharmaceutics. 11, 7, 349.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Breakthroughs in medicinal chemistry: New targets and mechanisms, new drugs, new hopes-4

Mangoni, A. A., Guillou, C., Eynde, J. J. V., Hulme, C., Jampilek, J., Li, W., Prokai-Tatrai, K., Rautio, J., Collina, S., Tuccinardi, T., Sousa, M. E., Sabatier, J. M., Galdiero, S., Karaman, R., Kokotos, G., Torri, G., Javier Luque, F., Helena Vasconcelos, M., Hadjipavlou-Litina, D., Siciliano, C. & 5 others, Gütschow, M., Ragno, R., Gomes, P. A. C., Agrofoglio, L. A. & Muñoz-Torrero, D., 1 Jan 2019, In : Molecules. 24, 1, p. 1-12 12 p.

Research output: Contribution to journalReview article

Breakthroughs in medicinal chemistry: New targets and mechanisms, New Drugs, New Hopes-5

Mangoni, A. A., Eynde, J. J. V., Jampilek, J., Hadjipavlou-Litina, D., Liu, H., Reynisson, J., Sousa, M. E., Gomes, P. A. C., Prokai-Tatrai, K., Tuccinardi, T., Sabatier, J. M., Luque, F. J., Rautio, J., Karaman, R., Vasconcelos, M. H., Gemma, S., Galdiero, S., Hulme, C., Collina, S., Gütschow, M. & 6 others, Kokotos, G., Siciliano, C., Capasso, R., Agrofoglio, L. A., Ragno, R. & Muñoz-Torrero, D., 1 Jan 2019, In : Molecules. 24, 13, 2415.

Research output: Contribution to journalReview article

Open Access
2 Scopus citations

Cannabinoid-like effects of five novel carboxamide synthetic cannabinoids

Gatch, M. B. & Forster, M. J., Jan 2019, In : NeuroToxicology. 70, p. 72-79 8 p.

Research output: Contribution to journalArticle

6 Scopus citations

Chemerin-activated functions of CMKLR1 are regulated by G protein-coupled receptor kinase 6 (GRK6) and β-arrestin 2 in inflammatory macrophages

Serafin, D. S., Allyn, B., Sassano, M. F., Timoshchenko, R. G., Mattox, D., Brozowski, J. M., Siderovski, D. P., Truong, Y. K., Esserman, D., Tarrant, T. K. & Billard, M. J., Feb 2019, In : Molecular Immunology. 106, p. 12-21 10 p.

Research output: Contribution to journalArticle

Cholesterol sulfate alters astrocyte metabolism and provides protection against oxidative stress

Prah, J., Winters, A., Chaudhari, K., Hersh, J., Liu, R. & Yang, S. H., 15 Nov 2019, In : Brain Research. 1723, 146378.

Research output: Contribution to journalArticle

Circulating mitochondrial DNA: New indices of type 2 diabetes-related cognitive impairment in Mexican Americans

Silzer, T., Barber, R., Sun, J., Pathak, G., Johnson, L., O’Bryant, S. & Phillips, N., Mar 2019, In : PLoS ONE. 14, 3, e0213527.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations

Combination of clotam and vincristine enhances anti-proliferative effect in medulloblastoma cells

Patil, S., Sankpal, U. T., Hurtado, M., Bowman, W. P., Murray, J., Borgmann, K., Ghorpade, A., Sutphin, R., Eslin, D. & Basha, R., 15 Jul 2019, In : Gene. 705, p. 67-76 10 p.

Research output: Contribution to journalArticle

1 Scopus citations
Open Access