Institute for Healthy Aging

Research output

Research output per year 1979 2000 2002 2003 2004 2005 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2023

• 90241 Citations
• 132 h-index
• 1602 Article
• 174 Review article
• 36 Comment/debate
• 28 Chapter
• 79 More
  • 24 Conference contribution
  • 18 Letter
  • 17 Editorial
  • 11 Short survey
  • 3 Conference article
  • 2 Book
  • 2 Foreword/postscript
  • 2 Paper

Research output per year

Research output per year

Search results

• Cisplatin-Induced Kidney Toxicity: Potential Roles of Major NAD⁺-Dependent Enzymes and Plant-Derived Natural Products

  Iskander, A. & Yan, L. J., Aug 2022, In: Biomolecules. 12, 8, 1078.

  Research output: Contribution to journal › Review article › peer-review

  • Cisplatin 100%
  • NAD 94%
  • Biological Products 90%
  • Occurrence in Nature 76%
  • Nicotinamide Nucleotide 50%

• Blood-based biomarkers for Alzheimer disease: mapping the road to the clinic

  Hampel, H., O’Bryant, S. E., Molinuevo, J. L., Zetterberg, H., Masters, C. L., Lista, S., Kiddle, S. J., Batrla, R. & Blennow, K., 1 Nov 2018, In: Nature Reviews Neurology. 14, 11, p. 639-652 14 p.

  Research output: Contribution to journal › Review article › peer-review

  • Alzheimer Disease 100%
  • Biomarkers 83%
  • Amyloidogenic Proteins 43%
  • tau Proteins 40%
  • Precision Medicine 34%

• Alzheimer's Disease: A Journey from Amyloid Peptides and Oxidative Stress, to Biomarker Technologies and Disease Prevention Strategies-Gains from AIBL and DIAN Cohort Studies

  Martins, R. N., Villemagne, V., Sohrabi, H. R., Chatterjee, P., Shah, T. M., Verdile, G., Fraser, P., Taddei, K., Gupta, V. B., Rainey-Smith, S. R., Hone, E., Pedrini, S., Lim, W. L., Martins, I., Frost, S., Gupta, S., O'Bryant, S., Rembach, A., Ames, D., Ellis, K., & 17 othersFuller, S. J., Brown, B., Gardener, S. L., Fernando, B., Bharadwaj, P., Burnham, S., Laws, S. M., Barron, A. M., Goozee, K., Wahjoepramono, E. J., Asih, P. R., Doecke, J. D., Salvado, O., Bush, A. I., Rowe, C. C., Gandy, S. E. & Masters, C. L., 2018, In: Journal of Alzheimer's Disease. 62, 3, p. 965-992 28 p.

  Research output: Contribution to journal › Review article › peer-review

  • dementia 100%
  • Amyloid 94%
  • Alzheimer Disease 77%
  • Oxidative Stress 72%
  • Cohort Studies 67%

• Neuropsychology of migraine: Present status and future directions

  O'Bryant, S., Marcus, D. A., Rains, J. C. & Penzien, D. B., 1 May 2005, In: Expert Review of Neurotherapeutics. 5, 3, p. 363-370 8 p.

  Research output: Contribution to journal › Review article › peer-review

  • Neuropsychology 100%
  • Migraine Disorders 76%
  • Direction compound 54%
  • Neuroimaging 27%
  • Headache 25%

• β-Secretase1 biological markers for Alzheimer’s disease: state-of-art of validation and qualification

  for the Alzheimer’s Precision Medicine Initiative (APMI), 1 Dec 2020, In: Alzheimer's Research and Therapy. 12, 1, 130.

  Research output: Contribution to journal › Review article › peer-review

  • Alzheimer Disease 100%
  • Biomarkers 83%
  • Amyloid 17%
  • Cerebrospinal Fluid 16%
  • Proteins 13%

• Innovative diagnostic tools for early detection of Alzheimer's disease

  Laske, C., Sohrabi, H. R., Frost, S. M., López-De-Ipiña, K., Garrard, P., Buscema, M., Dauwels, J., Soekadar, S. R., Mueller, S., Linnemann, C., Bridenbaugh, S. A., Kanagasingam, Y., Martins, R. N. & O'bryant, S. E., 1 May 2015, In: Alzheimer's and Dementia. 11, 5, p. 561-578 18 p.

  Research output: Contribution to journal › Review article › peer-review

  • dementia 100%
  • diagnostic 84%
  • Early Diagnosis 80%
  • Alzheimer Disease 77%
  • blood tests 30%

• The Alzheimer's Biomarker Consortium-Down Syndrome: Rationale and methodology

  the Alzheimer's Biomarker Consortium-Down Syndrome (ABC-DS), 2020, In: Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring. 12, 1, e12065.

  Research output: Contribution to journal › Review article › peer-review

  • Down Syndrome 100%
  • Alzheimer Disease 74%
  • Biomarkers 62%
  • Disease Progression 25%
  • Neuropathology 17%

• Renal-Protective Roles of Lipoic Acid in Kidney Disease

  Kamt, S. F., Liu, J. & Yan, L. J., Apr 2023, In: Nutrients. 15, 7, 1732.

  Research output: Contribution to journal › Review article › peer-review

  • lipoic acid 100%
  • Thioctic Acid 93%
  • kidney diseases 89%
  • Kidney Diseases 73%
  • kidneys 50%

• The negative and detrimental effects of high fructose on the liver, with special reference to metabolic disorders

  Mai, B. H. & Yan, L. J., 2019, In: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy. 12, p. 821-826 6 p.

  Research output: Contribution to journal › Review article › peer-review

  • Fructose 100%
  • Liver 45%
  • Insulin Resistance 14%
  • Eating 13%
  • Obesity 12%

• Optimizing the respiratory pump: Harnessing inspiratory resistance to treat systemic hypotension

  Convertino, V. A., Ryan, K. L., Rickards, C. A., Glorsky, S. L., Idris, A. H., Yannopoulos, D., Metzger, A. & Lurie, K. G., Jun 2011, In: Respiratory Care. 56, 6, p. 846-857 12 p.

  Research output: Contribution to journal › Review article › peer-review

  • Hypotension 100%
  • Pressure 55%
  • Respiration 35%
  • Heat Stroke 31%
  • Cardiac Volume 27%

• Integrative cerebral blood flow regulation in ischemic stroke

  Fan, J. L., Brassard, P., Rickards, C. A., Nogueira, R. C., Nasr, N., McBryde, F. D., Fisher, J. P. & Tzeng, Y. C., Mar 2022, In: Journal of Cerebral Blood Flow and Metabolism. 42, 3, p. 387-403 17 p.

  Research output: Contribution to journal › Review article › peer-review

  • Cerebrovascular Circulation 100%
  • Stroke 70%
  • Perfusion 31%
  • Blood Pressure 26%
  • Collateral Circulation 26%

• Estrogens as protectants of the neurovascular unit against ischemic stroke

  Yang, S. H., Liu, R., Perez, E. J., Wang, X. & Simpkins, J. W., Apr 2005, In: Current Drug Targets: CNS and Neurological Disorders. 4, 2, p. 169-177 9 p.

  Research output: Contribution to journal › Review article › peer-review

  • Estrogens 100%
  • Stroke 83%
  • Mitochondria 33%
  • Neuroprotective Agents 20%
  • Microglia 20%

• The reciprocal relationship between cardiac baroreceptor sensitivity and cerebral autoregulation during simulated hemorrhage in humans

  Rosenberg, A. J., Kay, V. L., Anderson, G. K., Luu, M. L., Barnes, H. J., Sprick, J. D., Alvarado, H. B. & Rickards, C. A., Sep 2022, In: Autonomic Neuroscience: Basic and Clinical. 241, 103007.

  Research output: Contribution to journal › Review article › peer-review

  • Pressoreceptors 100%
  • Baroreflex 78%
  • Lower Body Negative Pressure 76%
  • Arterial Pressure 64%
  • Homeostasis 58%

• Potential biochemical mechanisms of brain injury in diabetes mellitus

  Ma, W. X., Tang, J., Lei, Z. W., Li, C. Y., Zhao, L. Q., Lin, C., Sun, T., Li, Z. Y., Jiang, Y. H., Jia, J. T., Liang, C. Z., Liu, J. H. & Yan, L. J., 2020, In: Aging and Disease. 11, 4, p. 978-987 10 p.

  Research output: Contribution to journal › Review article › peer-review

  • Brain Injuries 100%
  • Cognitive Dysfunction 84%
  • Diabetes Mellitus 82%
  • Sample Size 45%
  • Alzheimer Disease 40%

• Transfer function analysis of dynamic cerebral autoregulation: A white paper from the International Cerebral Autoregulation Research Network

  international Cerebral Autoregulation Research Network (CARNet), 2015, In: Journal of Cerebral Blood Flow and Metabolism. 36, 4, p. 665-680 16 p.

  Research output: Contribution to journal › Review article › peer-review

  • Homeostasis 100%
  • Blood Pressure 43%
  • Cerebrovascular Circulation 21%
  • Perfusion 17%
  • Brain 11%

• Protein redox modification as a cellular defense mechanism against tissue ischemic injury

  Yan, L. J., 2014, In: Oxidative Medicine and Cellular Longevity. 2014, 343154.

  Research output: Contribution to journal › Review article › peer-review

  • Oxidation-Reduction 100%
  • Modification 57%
  • Wounds and Injuries 50%
  • Protein 43%
  • Proteins 38%

• Vagus nerve stimulation as a promising adjunctive treatment for ischemic stroke

  Ma, J., Qiao, P., Li, Q., Wang, Y., Zhang, L., Yan, L. J. & Cai, Z., Dec 2019, In: Neurochemistry International. 131, 104539.

  Research output: Contribution to journal › Review article › peer-review

  • Vagus Nerve Stimulation 100%
  • Stroke 51%
  • Neuronal Plasticity 15%
  • Therapeutics 12%
  • Memory Disorders 8%

• Advanced technology development for remote triage applications in bleeding combat casualties.

  Ryan, K. L., Rickards, C. A., Hinojosa-Laborde, C., Gerhardt, R. T., Cain, J. & Convertino, V. A., 2011, In: U.S. Army Medical Department journal. p. 61-72 12 p.

  Research output: Contribution to journal › Review article › peer-review

  • Industrial Development 100%
  • Triage 80%
  • Hemorrhage 46%
  • Wearable Electronic Devices 21%
  • Exercise 18%

• The effect of age, sex and strains on the performance and outcome in animal models of stroke

  Zhang, H., Lin, S., Chen, X., Gu, L., Zhu, X., Zhang, Y., Reyes, K., Wang, B. & Jin, K., Jul 2019, In: Neurochemistry International. 127, p. 2-11 10 p.

  Research output: Contribution to journal › Review article › peer-review

  • Animal Models 100%
  • Stroke 94%
  • Animals 27%
  • Rodentia 22%
  • Neurochemistry 18%

• Transfer function analysis of dynamic cerebral autoregulation: A CARNet white paper 2022 update

  on behalf of the Cerebrovascular Research Network (CARNet), Jan 2023, In: Journal of Cerebral Blood Flow and Metabolism. 43, 1, p. 3-25 23 p.

  Research output: Contribution to journal › Review article › peer-review

  • Homeostasis 100%
  • Cerebrovascular Circulation 98%
  • Arterial Pressure 55%
  • Guidelines 43%
  • Intracranial Pressure 37%

• Redox imbalance stress in diabetes mellitus: Role of the polyol pathway

  Yan, L. J., Mar 2018, In: Animal Models and Experimental Medicine. 1, 1, p. 7-13 7 p.

  Research output: Contribution to journal › Review article › peer-review

  • polyol 100%
  • diabetes mellitus 93%
  • Aldose 92%
  • polyols 81%
  • Fructose 76%

• NADH/NAD⁺ redox imbalance and diabetic kidney disease

  Yan, L. J., May 2021, In: Biomolecules. 11, 5, 730.

  Research output: Contribution to journal › Review article › peer-review

  • Diabetic Nephropathies 100%
  • NAD 96%
  • Oxidative Stress 93%
  • Dialysis 92%
  • Superoxide 92%

• Notch signaling and neurogenesis in normal and stroke brain

  Xiao, M. J., Han, Z., Shao, B. & Jin, K., 2009, In: International Journal of Physiology, Pathophysiology and Pharmacology. 1, 2, p. 192-202 11 p.

  Research output: Contribution to journal › Review article › peer-review

  • Neurogenesis 100%
  • Stroke 64%
  • Adult Stem Cells 54%
  • Brain 46%
  • Stem Cells 34%

• Folic acid-induced animal model of kidney disease

  Yan, L. J., Dec 2021, In: Animal Models and Experimental Medicine. 4, 4, p. 329-342 14 p.

  Research output: Contribution to journal › Review article › peer-review

  • kidney diseases 100%
  • Folic Acid 91%
  • folic acid 87%
  • Kidney Diseases 82%
  • animal models 68%

• Use of advanced machine-learning techniques for noninvasive monitoring of hemorrhage

  Convertino, V. A., Moulton, S. L., Grudic, G. Z., Rickards, C. A., Hinojosa-Laborde, C., Gerhardt, R. T., Blackbourne, L. H. & Ryan, K. L., Jul 2011, In: Journal of Trauma - Injury, Infection and Critical Care. 71, SUPPL. 1, p. S25-S32

  Research output: Contribution to journal › Review article › peer-review

  • Machine Learning 100%
  • Blood Volume 91%
  • Hemorrhage 57%
  • Hemodynamics 52%
  • Lower Body Negative Pressure 51%