Institute for Healthy Aging

Time course and magnitude of ventilatory and renal acid-base acclimatization following rapid ascent to and residence at 3,800 m over nine days

Bird, J. D., Leacy, J. K., Foster, G. E., Rickards, C. A., Wilson, R. J. A., O’Halloran, K. D., Jendzjowsky, N. G., Pentz, B. A., Byman, B. R. M., Thrall, S. F., Skalk, A. L., Hewitt, S. A., Steinback, C. D., Burns, D., Ondrus, P. & Day, T. A., Jun 2021, In: Journal of Applied Physiology. 130, 6, p. 1705-1715 11 p.

Research output: Contribution to journal › Article › peer-review

Role of Catalase in Oxidative Stress- And Age-Associated Degenerative Diseases

Nandi, A., Yan, L. J., Jana, C. K. & Das, N., 2019, In: Oxidative Medicine and Cellular Longevity. 2019, 9613090.

Research output: Contribution to journal › Article › peer-review

Level of Immersion in Virtual Environments Impacts the Ability to Assess and Teach Social Skills in Autism Spectrum Disorder

Miller, H. L. & Bugnariu, N. L., 1 Apr 2016, In: Cyberpsychology, Behavior, and Social Networking. 19, 4, p. 246-256 11 p.

Research output: Contribution to journal › Article › peer-review

Medical comorbidities and ethnicity impact plasma Alzheimer's disease biomarkers: Important considerations for clinical trials and practice

for the HABS-HD Study Team, Jan 2023, In: Alzheimer's and Dementia. 19, 1, p. 36-43 8 p.

Research output: Contribution to journal › Article › peer-review

Acute lower leg hot water immersion protects macrovascular dilator function following ischaemia–reperfusion injury in humans

Engelland, R. E., Hemingway, H. W., Tomasco, O. G., Olivencia-Yurvati, A. H. & Romero, S. A., 1 Feb 2020, In: Experimental physiology. 105, 2, p. 302-311 10 p.

Research output: Contribution to journal › Article › peer-review

Identification of trans-acting factors that interact with cis-acting elements present in the first nontranslated exon of the human apolipoprotein B gene

Chuang, S. S. & Das, H. K., 27 Mar 1996, In: Biochemical and Biophysical Research Communications. 220, 3, p. 553-562 10 p.

Research output: Contribution to journal › Article › peer-review

Transcriptional regulation of the apolipoprotein B100 gene: Purification and characterization of trans-acting factor BRF-2

Zhuang, H., Chuang, S. S. & Das, H. K., Jul 1992, In: Molecular and Cellular Biology. 12, 7, p. 3183-3191 9 p.

Research output: Contribution to journal › Article › peer-review

The Risk Factors of High Blood Pressure among Young Adults in the Tujia-Nationality Settlement of China

Liu, X., Xiang, Z., Shi, X., Schenck, H., Yi, X., Ni, R. & Liu, C., 2017, In: BioMed Research International. 2017, 8315603.

Research output: Contribution to journal › Article › peer-review

Modern biological theories of aging

Jin, K., 2010, In: Aging and Disease. 1, 2, p. 72-74 3 p.

Research output: Contribution to journal › Comment/debate

Neuroprotective Actions of Methylene Blue and Its Derivatives

Poteet, E., Winters, A., Yan, L. J., Shufelt, K., Green, K. N., Simpkins, J. W., Wen, Y. & Yang, S. H., 31 Oct 2012, In: PLoS ONE. 7, 10, e48279.

Research output: Contribution to journal › Article › peer-review

Streptozotocin-induced type 1 diabetes in rodents as a model for studying mitochondrial mechanisms of diabetic β cell glucotoxicity

Wu, J. & Yan, L. J., 2 Apr 2015, In: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy. 8, p. 181-188 8 p.

Research output: Contribution to journal › Review article › peer-review

Key signaling pathways in aging and potential interventions for healthy aging

Yu, M., Zhang, H., Wang, B., Zhang, Y., Zheng, X., Shao, B., Zhuge, Q. & Jin, K., Mar 2021, In: Cells. 10, 3, p. 1-26 26 p., 660.

Research output: Contribution to journal › Review article › peer-review

QEEG Signatures are Associated with Nonmotor Dysfunctions in Parkinson's Disease and Atypical Parkinsonism: An Integrative Analysis

Liu, H., Huang, Z., Deng, B., Chang, Z., Yang, X., Guo, X., Yuan, F., Yang, Q., Wang, L., Zou, H., Li, M., Zhu, Z., Jin, K. & Wang, Q., 1 Feb 2023, In: Aging and Disease. 14, 1, p. 204-218 15 p.

Research output: Contribution to journal › Article › peer-review

Early role of vascular dysregulation on late-onset Alzheimer's disease based on multifactorial data-driven analysis

The Alzheimer's Disease Neuroimaging Initiative, 21 Jun 2016, In: Nature Communications. 7, 11934.

Research output: Contribution to journal › Article › peer-review

Changes in carnitine palmitoyltransferase-i mrna abundance produced by hyperthyroidism and hypothyroidism parallel changes in activity

Mynatt, R. L., Park, E. A., Thorngate, F. E., Das, H. K. & Cook, G. A., 15 Jun 1994, In: Biochemical and Biophysical Research Communications. 201, 2, p. 932-937 6 p.

Research output: Contribution to journal › Article › peer-review

Pattern Discovery in Brain Imaging Genetics via SCCA Modeling with a Generic Non-convex Penalty

Du, L., Liu, K., Yao, X., Yan, J., Risacher, S. L., Han, J., Guo, L., Saykin, A. J., Shen, L., Weiner, M. W., Aisen, P., Petersen, R., Jack, C. R., Jagust, W., Trojanowki, J. Q., Toga, A. W., Beckett, L., Green, R. C., Morris, J. & Shaw, L. M. & 293 others, Khachaturian, Z., Sorensen, G., Carrillo, M., Kuller, L., Raichle, M., Paul, S., Davies, P., Fillit, H., Hefti, F., Holtzman, D., Mesulam, M. M., Potter, W., Snyder, P., Schwartz, A., Montine, T., Thomas, R. G., Donohue, M., Walter, S., Gessert, D., Sather, T., Jiminez, G., Balasubramanian, A. B., Mason, J., Sim, I., Harvey, D., Bernstein, M., Fox, N., Thompson, P., Schuff, N., Decarli, C., Borowski, B., Gunter, J., Senjem, M., Vemuri, P., Jones, D., Kantarci, K., Ward, C., Koeppe, R. A., Foster, N., Reiman, E. M., Chen, K., Mathis, C., Landau, S., Cairns, N. J., Franklin, E., Taylor-Reinwald, L., Lee, V., Korecka, M., Figurski, M., Crawford, K., Neu, S., Foroud, T. M., Potkin, S., Faber, K., Kim, S., Nho, K., Thal, L., Buckholtz, N., Albert, M., Frank, R., Hsiao, J., Kaye, J., Quinn, J., Silbert, L., Lind, B., Carter, R., Dolen, S., Schneider, L. S., Pawluczyk, S., Beccera, M., Teodoro, L., Spann, B. M., Brewer, J., Vanderswag, H., Fleisher, A., Heidebrink, J. L., Lord, J. L., Mason, S. S., Albers, C. S., Knopman, D., Johnson, K., Doody, R. S., Villanueva-Meyer, J., Pavlik, V., Shibley, V., Chowdhury, M., Rountree, S., Dang, M., Stern, Y., Honig, L. S., Bell, K. L., Ances, B., Carroll, M., Creech, M. L., Franklin, E., Mintun, M. A., Schneider, S., Oliver, A., Marson, D., Geldmacher, D., Love, M. N., Griffith, R., Clark, D., Brockington, J., Roberson, E., Grossman, H., Mitsis, E., Shah, R. C., Detoledo-Morrell, L., Duara, R., Greig-Custo, M. T., Barker, W., Onyike, C., D'Agostino, D., Kielb, S., Sadowski, M., Sheikh, M. O., Ulysse, A., Gaikwad, M., Murali Doraiswamy, P., Petrella, J. R., Borges-Neto, S., Wong, T. Z., Coleman, E., Arnold, S. E., Karlawish, J. H., Wolk, D. A., Clark, C. M., Smith, C. D., Jicha, G., Hardy, P., Sinha, P., Oates, E., Conrad, G., Lopez, O. L., Oakley, M. A., Simpson, D. M., Porsteinsson, A. P., Goldstein, B. S., Martin, K., Makino, K. M., Ismail, M. S., Brand, C., Preda, A., Nguyen, D., Womack, K., Mathews, D., Quiceno, M., Levey, A. I., Lah, J. J., Cellar, J. S., Burns, J. M., Swerdlow, R. H., Brooks, W. M., Apostolova, L., Tingus, K., Woo, E., Silverman, D. H. S., Lu, P. H., Bartzokis, G., Graff-Radford, N. R., Parfitt, F., Poki-Walker, K., Farlow, M. R., Marie Hake, A., Matthews, B. R., Brosch, J. R., Herring, S., Van Dyck, C. H., Carson, R. E., MacAvoy, M. G., Varma, P., Chertkow, H., Bergman, H., Hosein, C., Black, S., Stefanovic, B., Caldwell, C., Robin Hsiung, G. Y., Mudge, B., Sossi, V., Feldman, H., Assaly, M., Finger, E., Pasternack, S., Rachisky, I., Rogers, J., Trost, D., Kertesz, A., Bernick, C., Munic, D., Rogalski, E., Lipowski, K., Weintraub, S., Bonakdarpour, B., Kerwin, D., Wu, C. K., Johnson, N., Sadowsky, C., Villena, T., Scott Turner, R., Johnson, K., Reynolds, B., Sperling, R. A., Johnson, K. A., Marshall, G., Yesavage, J., Taylor, J. L., Lane, B., Rosen, A., Tinklenberg, J., Sabbagh, M. N., Belden, C. M., Jacobson, S. A., Sirrel, S. A., Kowall, N., Killiany, R., Budson, A. E., Norbash, A., Lynn Johnson, P., Obisesan, T. O., Wolday, S., Allard, J., Lerner, A., Ogrocki, P., Tatsuoka, C., Fatica, P., Fletcher, E., Maillard, P., Olichney, J., Decarli, C., Carmichael, O., Kittur, S., Borrie, M., Lee, T. Y., Bartha, R., Johnson, S., Asthana, S., Carlsson, C. M., Tariot, P., Burke, A., Milliken, A. M., Trncic, N., Fleisher, A., Reeder, S., Bates, V., Capote, H., Rainka, M., Scharre, D. W., Kataki, M., Kelly, B., Zimmerman, E. A., Celmins, D., Brown, A. D., Pearlson, G. D., Blank, K., Anderson, K., Flashman, L. A., Seltzer, M., Hynes, M. L., Santulli, R. B., Sink, K. M., Gordineer, L., Williamson, J. D., Garg, P., Watkins, F., Ott, B. R., Tremont, G., Daiello, L. A., Salloway, S., Malloy, P., Correia, S., Rosen, H. J., Miller, B. L., Perry, D., Mintzer, J., Spicer, K., Bachman, D., Pomara, N., Hernando, R., Sarrael, A., Schultz, S. K., Ekstam Smith, K., Koleva, H., Nam, K. W., Shim, H., Relkin, N., Chaing, G., Lin, M., Ravdin, L., Smith, A., Ashok Raj, B. & Fargher, K., 1 Dec 2017, In: Scientific Reports. 7, 1, 14052.

Research output: Contribution to journal › Article › peer-review

Association of plasma neurofilament light with neurodegeneration in patients with Alzheimer disease

Alzheimer's Disease Neuroimaging Initiative, May 2017, In: JAMA Neurology. 74, 5, p. 557-566 10 p.

Research output: Contribution to journal › Article › peer-review

Blood-based biomarker screening with agnostic biological definitions for an accurate diagnosis within the dimensional spectrum of neurodegenerative diseases

for the Alzheimer Precision Medicine Initiative (APMI), 2018, Methods in Molecular Biology. Humana Press Inc., p. 139-155 17 p. (Methods in Molecular Biology; vol. 1750).

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

Combining injectable plasma scaffold with mesenchymal stem/stromal cells for repairing infarct cavity after ischemic stroke

Zhang, H., Sun, F., Wang, J., Xie, L., Pan, M., Shao, B., Yang, G. Y., Yang, S. H., ZhuGe, Q. & Jin, K., 2017, In: Aging and Disease. 8, 2, p. 203-214 12 p.

Research output: Contribution to journal › Article › peer-review

Transplantation of Roxadustat-preconditioned bone marrow stromal cells improves neurological function recovery through enhancing grafted cell survival in ischemic stroke rats

Chen, J., Lin, X., Yao, C., Bingwa, L. A., Wang, H., Lin, Z., Jin, K., Zhuge, Q. & Yang, S., Oct 2022, In: CNS Neuroscience and Therapeutics. 28, 10, p. 1519-1531 13 p.

Research output: Contribution to journal › Article › peer-review

Transplanted neural stem cells modulate regulatory T, γδ T cells and corresponding cytokines after intracerebral hemorrhage in rats

Gao, L., Lu, Q., Huang, L. J., Ruan, L. H., Yang, J. J., Huang, W. L., ZhuGe, W. S., Zhang, Y. L., Fu, B., Jin, K. L. & ZhuGe, Q. C., 13 Mar 2014, In: International journal of molecular sciences. 15, 3, p. 4431-4441 11 p.

Research output: Contribution to journal › Article › peer-review

Inhibition of mammalian target of rapamycin improves neurobehavioral deficit and modulates immune response after intracerebral hemorrhage in rat

Lu, Q., Gao, L., Huang, L., Ruan, L., Yang, J., Huang, W., Li, Z., Zhang, Y., Jin, K. & Zhuge, Q., 6 Mar 2014, In: Journal of neuroinflammation. 11, 44.

Research output: Contribution to journal › Article › peer-review

Type 2 diabetes mellitus, brain atrophy, and cognitive decline

Moran, C., Beare, R., Wang, W., Callisaya, M., Srikanth, V., Weiner, M., Aisen, P., Petersen, R., Jack, C. R., Jagust, W., Trojanowki, J. Q., Toga, A. W., Beckett, L., Green, R. C., Saykin, A. J., Morris, J. C., Liu, E., Montine, T., Gamst, A. & Thomas, R. G. & 233 others, Donohue, M., Walter, S., Gessert, D., Sather, T., Harvey, D., Kornak, J., Dale, A., Bernstein, M., Felmlee, J., Fox, N., Thompson, P., Schuff, N., Alexander, G., Decarli, C., Bandy, D., Koeppe, R. A., Foster, N., Reiman, E. M., Chen, K., Mathis, C., Cairns, N. J., Taylor-Reinwald, L., Trojanowki, J. Q., Shaw, L., Lee, V. M. Y., Korecka, M., Crawford, K., Neu, S., Foroud, T. M., Potkin, S., Shen, L., Kachaturian, Z., Frank, R., Snyder, P. J., Molchan, S., Kaye, J., Quinn, J., Lind, B., Dolen, S., Schneider, L. S., Pawluczyk, S., Spann, B. M., Brewer, J., Vanderswag, H., Heidebrink, J. L., Lord, J. L., Johnson, K., Doody, R. S., Villanueva-Meyer, J., Chowdhury, M., Stern, Y., Honig, L. S., Bell, K. L., Ances, B., Carroll, M., Leon, S., Mintun, M. A., Schneider, S., Marson, D., Griffith, R., Clark, D., Grossman, H., Mitsis, E., Romirowsky, A., Detoledo-Morrell, L., Shah, R. C., Duara, R., Varon, D., Roberts, P., Albert, M., Onyike, C., Kielb, S., Rusinek, H., De Leon, M. J., Glodzik, L., De Santi, S., Doraiswamy, P. M., Petrella, J. R., Coleman, R. E., Arnold, S. E., Karlawish, J. H., Wolk, D., Smith, C. D., Jicha, G., Hardy, P., Lopez, O. L., Oakley, M., Simpson, D. M., Porsteinsson, A. P., Goldstein, B. S., Martin, K., Makino, K. M., Ismail, M. S., Brand, C., Mulnard, R. A., Thai, G., McAdams-Ortiz, C., Womack, K., Mathews, D., Quiceno, M., Diaz-Arrastia, R., King, R., Weiner, M., Martin-Cook, K., Devous, M., Levey, A. I., Lah, J. J., Cellar, J. S., Burns, J. M., Anderson, H. S., Swerdlow, R. H., Apostolova, L., Lu, P. H., Bartzokis, G., Silverman, D. H. S., Graff-Radford, N. R., Parfitt, F., Johnson, H., Farlow, M. R., Hake, A. M., Matthews, B. R., Herring, S., Van Dyck, C. H., Carson, R. E., Macavoy, M. G., Chertkow, H., Bergman, H., Hosein, C., Black, S., Stefanovic, B., Caldwell, C., Robin Hsiung, G. Y., Feldman, H., Mudge, B., Assaly, M., Kertesz, A., Rogers, J., Trost, D., Bernick, C., Munic, D., Kerwin, D., Mesulam, M. M., Lipowski, K., Wu, C. K., Johnson, N., Sadowsky, C., Martinez, W., Villena, T., Turner, R. S., Johnson, K., Reynolds, B., Sperling, R. A., Johnson, K. A., Marshall, G., Frey, M., Yesavage, J., Taylor, J. L., Lane, B., Rosen, A., Tinklenberg, J., Sabbagh, M., Belden, C., Jacobson, S., Kowall, N., Killiany, R., Budson, A. E., Norbash, A., Johnson, P. L., Obisesan, T. O., Wolday, S., Bwayo, S. K., Lerner, A., Hudson, L., Ogrocki, P., Fletcher, E., Carmichael, O., Olichney, J., Kittur, S., Borrie, M., Bartha, D. R., Johnson, S., Asthana, S., Carlsson, C. M., Potkin, S. G., Preda, A., Nguyen, D., Tariot, P., Fleisher, A., Reeder, S., Bates, V., Capote, H., Rainka, M., Scharre, D. W., Kataki, M., Zimmerman, E. A., Celmins, D., Brown, A. D., Pearlson, G. D., Blank, K., Anderson, K., Santulli, R. B., Schwartz, E. S., Sink, K. M., Williamson, J. D., Garg, P., Watkins, F., Ott, B. R., Querfurth, H., Tremont, G., Salloway, S., Malloy, P., Correia, S., Rosen, H. J., Miller, B. L., Mintzer, J., Longmire, C. F., Spicer, K., Finger, E., Rachinsky, I., Drost, D., Pomara, N., Hernando, R., Sarrael, A., Schultz, S. K., Boles Ponto, L. L., Shim, H., Smith, K. E., Relkin, N., Chaing, G., Raudin, L., Smith, A., Fargher, K. & Raj, B. A., 19 Feb 2019, In: Neurology. 92, 8, p. E823-E830

Research output: Contribution to journal › Article › peer-review

Estrogen protection in Friedreich's ataxia skin fibroblasts

Richardson, T. E., Yang, S. H., Wen, Y. & Simpkins, J. W., Jul 2011, In: Endocrinology. 152, 7, p. 2742-2749 8 p.

Research output: Contribution to journal › Article › peer-review

Coupling of neurogenesis and angiogenesis after ischemic stroke

Ruan, L., Wang, B., Zhuge, Q. & Jin, K., 14 Oct 2015, In: Brain Research. 1623, p. 166-173 8 p.

Research output: Contribution to journal › Article › peer-review

Institute for Healthy Aging

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