Institute for Healthy Aging

Projects

Projects per year 1986 2012 2013 2014 2015 2016 2017 2019 2029

• 14 Active
• 327 Finished

Projects per year

Search results

• Neuroglobin: Cell Membrane and Neuroprotection

  Yang, S. (PI), Liu, R. (CoI) & Jin, K. (CoI)

  NINDS: Neurological Disorders & Stroke

  1/07/14 → 31/05/19

  Project: Research

• Potential Therapeutic Benefits of Remote Ischemic Preconditioning vs. Occlusive Exercise - An Acute Study (For: Justin Sprick)

  Rickards, C. (PI)

  NHLBI: Nat Heart, Lung & Blood Institute

  1/06/17 → 31/05/19

  Project: Research

• A Phase II, Multicenter, Randomized, Double-blind, Parallel-group, Placebo-controlled Study to Investigate the Efficacy and Safety of RO4602522 Added to Background Alzheimer¿s Disease Therapy in Patients with Moderate Severity Alzheimer¿s Disease

  Knebl, J. (PI)

  Hoffmann-La Roche Inc.

  25/10/13 → 31/03/19

  Project: Research

• Therapeutic Effects of Exercise in Adults with Amnestic Mild Cognitive Impairment

  O'Bryant, S. (PI) & Johnson, L. (CoI)

  University of California, San Diego

  15/03/16 → 28/02/19

  Project: Research

• Direct Reprogramming of Reactive Astrocytes after Stroke

  Jin, K. (PI) & Uteshev, V. (CoI)

  William & Ella Owens Med Research Foun

  1/03/18 → 28/02/19

  Project: Research

• Six and Twelve Month Outcome Effectiveness of Cognitive Program Interventions in Veterans

  Nejtek, V. (PI)

  Recovery Resource Council

  1/09/17 → 31/12/18

  Project: Research

• Magnetically Tissue Plasminogen Activator-Loaded Fe304 Nanorods Improve Thrombolysis Rates after Ischemic Stroke (Jiangnan Hu)

  Jin, K. (PI)

  Sigma Xi

  1/01/18 → 31/12/18

  Project: Research

• AMPK and Cerebellar Aging

  Yang, S. (PI) & Sumien, N. (CoI)

  William & Ella Owens Med Research Foun

  1/12/16 → 31/12/18

  Project: Research

• Susceptibility of Cerebellar Purkinje Cells to Oxidative Stress

  Huang, R.-Q. (PI) & Yang, S. (CoI)

  William & Ella Owens Med Research Foun

  1/10/17 → 31/12/18

  Project: Research

• D3 Receptor Compounds for the Treatment of Psychostimulant Abuse

  Luedtke, R. (PI)

  NIDA: National Institute on Drug Abuse

  15/02/15 → 30/11/18

  Project: Research

• Novel Mechanistic Targets of Steroid Hormones in the Brain - Core B

  Forster, M. (PI), Shetty, R. (CoI), Yang, S. (CoI), Liu, R. (CoI) & Sumien, N. (CoI)

  NIA: National Institute on Aging

  1/12/12 → 30/11/18

  Project: Research

• Novel Mechanistic Targets of Steroid Hormones in the Brain

  ALLERAND, D. (CoPI), Koulen, P. (CoPI), SIMPKINS, J. (CoPI), FORSTER, M. (CoPI), Prókai, L. (CoPI), SINGH, M. (CoPI), Prókai, L. (CoPI), Koulen, P. (CoPI), Singh, M. (PI), Forster, M. (CoPI) & Prokai, L. (CoPI)

  15/08/07 → 30/11/18

  Project: Research

  • Mechanistic Target 100%
  • Steroid Hormones 100%
  • Estrogen 100%
  • Alzheimer's Disease 100%
  • Steroid Hormone 100%

• Assessment of the Effects of Novel Nestle Diets on balance (Phase I) and cognitive function (Phase II) in Female 5XFAD Transgenic Mice (Project VII)

  Yang, S. (PI) & Liu, R. (CoI)

  Nestle Purina

  18/10/16 → 18/10/18

  Project: Research

• IGF::OT::IGF: Base Award for Using Rodent Behavioral Models to Identify Substance Abuse Pharmacotherapies

  Forster, M. (PI)

  1/10/17 → 30/09/18

  Project: Research

  • Pharmacotherapy 100%
  • Behavioral Model 100%
  • Substance Abuse 100%
  • Drug Discrimination 100%
  • Rodents 100%

• Inflammation as a Pathway for the Depression-cognition Link

  Johnson, L. (PI) & O'Bryant, S. (CoI)

  National Alzheimer's Association

  1/10/16 → 30/09/18

  Project: Research

• FY 13 Rodent Testing to Identify Pharma. for Substance Dependence

  Forster, M. (PI)

  National Institute on Drug Abuse

  1/10/17 → 30/09/18

  Project: Research

  • Substance Dependence 100%
  • Rodents 100%
  • Pharma 100%
  • Conditioned Place Preference Test 100%
  • Conditioned Place Preference 100%

• Rodent Testing to Identify Pharmacotherapies for Substance Dependence

  Forster, M. (PI) & Gatch, M. (CoI)

  NIDA: National Institute on Drug Abuse

  4/01/16 → 20/09/18

  Project: Research

• Cocaine-induced Stroke Susceptibility: Brain Function and Metabolism Signaling Pathways

  Sumien, N. (PI), Forster, M. (CoI) & Yang, S. (CoI)

  Intramural Research(UNTHSC)

  1/05/16 → 31/08/18

  Project: Research

• Blood Biomarker Links Mild Traumatic Brain Injury to Alzheimer's Risk - Phase II

  Nejtek, V. (PI)

  J. E. S. Edwards Foundation

  1/09/16 → 31/08/18

  Project: Research

• Texas Consortium of Alzheimer's Disease Centers

  Barber, R. (PI) & Knebl, J. (CoI)

  Alzheimer's Disease Program

  1/09/17 → 31/08/18

  Project: Research

• Role of Transcellular Mitophagy in Diabetic Retinal Neurodegeneration

  Yan, L.-J. (PI) & Liu, Y. (CoI)

  Intramural Research(UNTHSC)

  1/09/16 → 31/08/18

  Project: Research

• Understanding Depression-Related Memory Loss among the Elderly "Proof of Concept"

  Johnson, L. (PI)

  J. E. S. Edwards Foundation

  1/09/16 → 31/08/18

  Project: Research

• Beneficial Effects of Dietary Soy Phytoestrogens on the Aging Female Brain

  Schreihofer, D. (PI)

  J. E. S. Edwards Foundation

  1/08/16 → 31/07/18

  Project: Research

• Intermittent Hypoxia - Novel Intervention for Treatment of Mild Cognitive Impairment

  Shi, X. (PI)

  Texas A&M Health Science Center

  1/10/15 → 30/07/18

  Project: Research

• NINDS Schrhfr 06/18

  Schreihofer, D. (PI)

  NINDS: Neurological Disorders & Stroke

  1/07/16 → 30/06/18

  Project: Research

• Translation of Evaluating Exercise-impact on Aging-related Motor Function Between Rats and Humans

  Salvatore, M. (PI) & Bugnariu, N. (CoI)

  Intramural Research(UNTHSC)

  1/01/17 → 30/06/18

  Project: Research

• Pyruvate-enriched Resuscitation to Reduce Inflammation and Free Radical Production During Simulated Hemorrhage

  Rickards, C. (PI), Yurvati, A. (CoI) & Mallet, R. (CoI)

  William & Ella Owens Med Research Foun

  1/06/17 → 30/06/18

  Project: Research

• Nanosensing of Oxidized Cell-free mtDNA: Biomarkers of Inflammation and Mitochondrial Dysfunction

  Phillips, N. (PI), Planz, J. (CoI) & Goulopoulou, S. (CoI)

  Intramural Research(UNTHSC)

  1/06/17 → 31/05/18

  Project: Research

• Prescribing patterns treating veterans (For: Scott Vicenzi )

  Nejtek, V. (PI)

  Intramural Research(UNTHSC)

  5/06/17 → 31/05/18

  Project: Research

• Evaluation of small molecules in ocular neovascularization (For: Daniel Larson)

  Acharya, S. (PI)

  Intramural Research(UNTHSC)

  5/06/17 → 31/05/18

  Project: Research

• Intermittent Hypoxia and Cardiovascular Function - The Effect of Age: Acute Cardiovascular response to Simulated OSA

  Shi, X. (PI)

  Intramural Research(UNTHSC)

  1/06/16 → 31/05/18

  Project: Research

• Cytokine Secretion in dopamine neurons (For: Jenny Trieu)

  Cunningham, R. (PI)

  Intramural Research(UNTHSC)

  5/06/17 → 31/05/18

  Project: Research

• Effects of antioxidants and exercise on protein oxidation (For: Saad Jafri)

  Sumien, N. (PI)

  Intramural Research(UNTHSC)

  5/06/17 → 31/05/18

  Project: Research

• Pilot Study on the Risks of Testosterone Replacement to the Brain

  Schreihofer, D. (PI), Sumien, N. (CoI) & Cunningham, R. (CoI)

  NIA: National Institute on Aging

  15/08/15 → 31/05/18

  Project: Research

• Pilot study on the risks of testosterone replacement to the brain

  Cunningham, R. (PI) & Schreihofer, D. (CoPI)

  National Institute on Aging

  15/08/15 → 31/05/18

  Project: Research

  • Current Estimation 100%
  • Over 45 100%
  • Total Testosterone 100%
  • Testosterone Replacement Therapy 100%
  • Hypogonadal Men 100%

• Oxidative stress and neuroprotection (For: Irfath Kahn)

  Yang, S. (PI)

  Intramural Research(UNTHSC)

  5/06/17 → 31/05/18

  Project: Research

• Efficacy and Safety of T-817MA in Patients with Mild to Moderate Alzheimer's Disease (US202)

  O'Bryant, S. (PI) & Knebl, J. (CoI)

  University of California, San Diego

  13/11/14 → 31/05/18

  Project: Research

• Impacts of the Systemic Milieu on Stroke Outcome

  Jin, K. (PI)

  NINDS: Neurological Disorders & Stroke

  1/05/16 → 30/04/18

  Project: Research

• Aging and Neurogenesis

  Jin, K. (PI)

  NIA: National Institute on Aging

  12/12/11 → 30/04/18

  Project: Research

• Potential Therapeutic Benefits of Remote Ischemic Preconditioning vs. Occlusive Exercise - An Acute Study

  Rickards, C. (PI)

  Intramural Research(UNTHSC)

  1/03/15 → 30/04/18

  Project: Research

• A Novel Mouse Model to Study Motoric Aging Induced by Benzodiazepine Abuse

  Jung, E. (PI) & Hall, J. (CoI)

  NIA: National Institute on Aging

  30/09/16 → 30/04/18

  Project: Research

• Sigma 1 Receptor as a Target for Repetitive Concussive Brain Injury

  Schreihofer, D. (PI), Luedtke, R. (CoI) & Sumien, N. (CoI)

  Intramural Research(UNTHSC)

  1/08/16 → 30/04/18

  Project: Research

• Neuroprotection of Nonfeminizing Estrogens Against Cognitive Deficits of Alzheimer's Disease

  Huang, R.-Q. (PI) & Sumien, N. (CoI)

  Texas A&M Health Science Center

  1/10/15 → 31/03/18

  Project: Research

• Dietary Targeting of Dihydrolipoamide Dehydrogenase for Stroke Tolerance

  Yan, L.-J. (PI) & Yang, S. (CoI)

  NINDS: Neurological Disorders & Stroke

  1/04/13 → 31/03/18

  Project: Research

• Dietary Targeting of Dihydrolipoamide Dehydrogenase for Stroke Tolerance

  Forster, M. (PI), Huang, R.-Q. (CoI) & Sumien, N. (CoI)

  NINDS: Neurological Disorders & Stroke

  1/04/13 → 31/03/18

  Project: Research

• Pulsatile Perfusion Therapy: A Novel Approach for Improving Cerebral Tissue Blood Flow and Oxygenation

  Rickards, C. (PI)

  Intramural Research(UNTHSC)

  1/07/16 → 28/02/18

  Project: Research

• Establishment of inducible astrocyte specific p38 MAPK knockout mouse line

  Yang, S. (PI)

  National Institute of Neurological Disorders and Stroke

  15/09/14 → 28/02/18

  Project: Research

  • Astrocytes 100%
  • P38 Mitogen-activated Protein Kinase (p38 MAPK) 100%
  • Knock-in Mouse Model 100%
  • P38 Mitogen-Activated Protein Kinases 100%
  • Astrocyte 100%

• Mitochondrial Function as a Mechanism for Diabetes-Related Cognitive Decline

  Phillips, N. (PI) & Phillips, N. (CoI)

  Intramural Research(UNTHSC)

  1/09/14 → 28/02/18

  Project: Research

• Establishment of Inducible Astrocyte Specific p38 MAPK Knockout Mouse Line

  Yang, S. (PI) & Liu, R. (CoI)

  NINDS: Neurological Disorders & Stroke

  15/09/14 → 28/02/18

  Project: Research

• High-Resolution Tandem Mass Spectrometer for Advanced Biomolecular Research

  Prokai, L. (PI), Forster, M. (CoI) & Cheng, E. Y. (CoI)

  Intramural Research(UNTHSC)

  27/01/17 → 31/01/18

  Project: Research